Nighoghossian N, Ruel J H, Ffrench P, Froment J C, Trouillas P
Service de Neurologie B, Hôpital Neurologique, Lyon.
Rev Neurol (Paris). 1990;146(3):221-3.
A 59-year old man developed subacute tetraparesis following severe sudden neck pain. MRI showed a subdural cervical hematoma. Prothrombin complex activity was low. An unusual coagulopathy after rodenticides exposure was found. Diphenacoum, an effective antagonist of vitamin K1, was present in the patients plasma. Specific medical management led to a complete recovery. Follow-up MRI seventy days later confirmed the complete disappearance of the hematoma.
一名59岁男性在突发严重颈部疼痛后出现亚急性四肢轻瘫。磁共振成像(MRI)显示颈段硬膜下血肿。凝血酶原复合物活性降低。发现该患者在接触杀鼠剂后出现了一种罕见的凝血病。患者血浆中存在敌鼠,它是维生素K1的有效拮抗剂。经过针对性的治疗,患者完全康复。70天后的随访MRI证实血肿已完全消失。