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日本尿石症的流行病学:一项按时间顺序和地域的研究。

Epidemiology of urolithiasis in Japan: a chronological and geographical study.

作者信息

Yoshida O, Okada Y

机构信息

Department of Urology, Faculty of Medicine, Kyoto University, Japan.

出版信息

Urol Int. 1990;45(2):104-11. doi: 10.1159/000281680.

Abstract

A nationwide survey on urolithiasis in Japan between 1965 through 1987 was carried out, succeeding the previous 1955 and 1966 studies, in an effort to evaluate chronological and geographical changes in urolithiasis among the Japanese people who are relatively racially homogenous and living with similar customs and habits, which have changed dramatically from the old Japanese to westernized modes in a very short period after the Second World War. Incidence of calcium-containing urinary stones in the upper urinary tract has been increasing in Japan since the Second World War with increasing westernization of life-style and industrialization, with the annual incidence of urolithiasis steadily increasing from 53.8/100,000 general population in 1965 to 92.5 in 1985. According to the data, 5.4% of the population may be expected to develop a urinary calculus at least once in their life time. Analysis of 69,949 stones obtained during the years from 1978 to 1987 with infrared analysis showed that 79.4% were calcium oxalate and/or calcium phosphate stones, 7.4% were struvite with or without carbonate apatite, 5.2% were uric acid or urate, and 1.0% were cystine. In the era of new treatment modalities such as the endourological surgery and the extracorporeal shock wave lithotripsy, open surgical treatments were replaced with new types of treatment in about 75% of the cases in 1985.

摘要

继1955年和1966年的研究之后,1965年至1987年在日本开展了一项关于尿石症的全国性调查,旨在评估尿石症在种族相对单一、生活习俗相似的日本人群中的时间和地域变化。自第二次世界大战后,日本人的生活方式在短时间内从传统模式急剧转变为西方化模式。自第二次世界大战以来,随着生活方式的西方化和工业化程度的提高,日本上尿路含钙尿路结石的发病率一直在上升,尿石症的年发病率从1965年每10万总人口中的53.8例稳步增至1985年的92.5例。根据这些数据,预计5.4%的人口一生中至少会患一次尿路结石。对1978年至1987年期间通过红外分析获得的69949块结石进行分析表明,79.4%为草酸钙和/或磷酸钙结石,7.4%为含或不含碳酸磷灰石的磷酸镁铵结石,5.2%为尿酸或尿酸盐结石,1.0%为胱氨酸结石。在诸如腔内泌尿外科手术和体外冲击波碎石术等新治疗方式的时代,1985年约75%的病例中,开放手术治疗被新型治疗方法所取代。

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