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老年人尿路结石的流行病学

Epidemiology of urolithiasis in the elderly.

作者信息

Kohri K, Ishikawa Y, Katoh Y, Kataoka K, Iguchi M, Yachiku S, Kurita T

机构信息

Department of Urology, Kinki University School of Medicine, Osaka, Japan.

出版信息

Int Urol Nephrol. 1991;23(5):413-21. doi: 10.1007/BF02583983.

Abstract

To estimate the epidemiology of upper urinary stones in the elderly, a total of 1,957 patients (1,349 men and 608 women) with urolithiasis were studied. The ratio of men to women was approximately 3:1 in middle-aged (between 30 and 59 years), 1:1 in young (29 or younger) and 1:1 in old patients (60 or older). Compared with the age distribution of the entire Japanese population, the incidence of urinary stones was very low in both male and female children, twice as high in middle-aged men, slightly higher in middle-aged women, and equal or slightly lower in the male and female elderly. Stones of calcium oxalate and uric acid occurred more frequently and those of calcium phosphate and struvite less frequently in men than in women. This tendency was especially obvious in the middle-aged. In the old generation, calcium oxalate stones occurred almost equally in men and women. Results of urinary stone analysis were similar among men of the three generations, although the incidence of uric acid stones increased with patient age. In women, however, the incidence of calcium oxalate was higher in the young and old generations, while that of calcium phosphate was higher in the middle-aged.

摘要

为评估老年上尿路结石的流行病学情况,我们对1957例尿路结石患者(1349例男性和608例女性)进行了研究。中年患者(30至59岁)中男女比例约为3:1,青年患者(29岁及以下)中男女比例为1:1,老年患者(60岁及以上)中男女比例也为1:1。与整个日本人口的年龄分布相比,尿路结石在男女儿童中的发病率都非常低,在中年男性中是其两倍,在中年女性中略高,在老年男性和女性中则相等或略低。草酸钙结石和尿酸结石在男性中比在女性中更常见,磷酸钙结石和鸟粪石结石在男性中比在女性中更少见。这种趋势在中年人群中尤为明显。在老年一代中,草酸钙结石在男性和女性中的发生率几乎相同。三代男性的尿路结石分析结果相似,尽管尿酸结石的发生率随患者年龄增加而上升。然而,在女性中,草酸钙结石在青年和老年一代中的发生率较高,而磷酸钙结石在中年女性中的发生率较高。

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