Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China.
Food Funct. 2013 Apr 25;4(4):530-8. doi: 10.1039/c2fo30252g. Epub 2013 Jan 10.
The consumption of tea and herbal infusions has increased rapidly in recent years. More and more people consume these infusions as daily beverages as well as for health purposes. The aim of this study was to supply new information on the antiproliferative function of these infusions for nutritionists and the general public. The in vitro antiproliferative activities of 60 different tea and herbal infusions on four cancer cell lines were evaluated by MTT assay. The results showed that some infusions strongly inhibited the proliferation of A549 (human lung cancer cells), MCF-7 (human breast cancer cells), HepG2 (human hepatoma cells) and HT-29 (human colon cancer cells), and decreased the viability of these cancer cell lines in a dose-dependent manner. In addition, some bioactive components in the infusions were also separated and determined by HPLC. The results suggested that some tea and herbal infusions may be potential dietary supplements for the prevention and treatment of cancer.
近年来，茶和草药浸剂的消费迅速增加。越来越多的人将这些浸剂作为日常饮料和保健饮品来消费。本研究旨在为营养师和公众提供这些浸剂的抗肿瘤增殖功能的新信息。通过 MTT 法评估了 60 种不同茶和草药浸剂对 4 种癌细胞系的体外抗肿瘤增殖活性。结果表明，一些浸剂强烈抑制 A549（人肺癌细胞）、MCF-7（人乳腺癌细胞）、HepG2（人肝癌细胞）和 HT-29（人结肠癌细胞）的增殖，并以剂量依赖的方式降低这些癌细胞系的活力。此外，还通过 HPLC 分离和测定了浸剂中的一些生物活性成分。结果表明，一些茶和草药浸剂可能是预防和治疗癌症的潜在膳食补充剂。
