Royal Orthopaedic Hospital, Bristol Road South, Northfield, Birmingham B31 2AP, UK.
Bone Joint J. 2013 Jan;95-B(1):127-31. doi: 10.1302/0301-620X.95B1.29131.
A total of 157 hindquarter amputations were carried out in our institution during the last 30 years. We have investigated the reasons why this procedure is still required and the outcome. This operation was used as treatment for 13% of all pelvic bone sarcomas. It was curative in 140 and palliative in 17, usually to relieve pain. There were 90 primary procedures (57%) with the remaining 67 following the failure of previous operations to control the disease locally. The indication for amputation in primary disease was for large tumours for which limb-salvage surgery was no longer feasible. The peri-operative mortality was 1.3% (n = 2) and major complications of wound healing or infection arose in 71 (45%) patients. The survival at five years after hindquarter amputation with the intent to cure was 45%, and at ten years 38%. Local recurrence occurred in 23 patients (15%). Phantom pain was a significant problem, and only 20% used their prosthesis regularly. Functional scores were a mean of 57%. With careful patient selection the oncological results and functional outcomes of hindquarter amputation justify its continued use.
在过去的 30 年中,我们机构共进行了 157 例后肢截肢手术。我们研究了为什么仍然需要进行这种手术以及手术的结果。这种手术用于治疗所有骨盆骨肉瘤的 13%。140 例是治愈性的,17 例是姑息性的,通常是为了缓解疼痛。90 例是原发性手术(57%),其余 67 例是在前次手术未能局部控制疾病后进行的。原发性疾病进行截肢的指征是肿瘤较大,无法进行保肢手术。围手术期死亡率为 1.3%(n=2),71 例(45%)患者出现伤口愈合或感染等严重并发症。意向治愈的后肢截肢术后 5 年生存率为 45%,10 年生存率为 38%。23 例患者(15%)出现局部复发。幻肢痛是一个严重的问题,只有 20%的患者定期使用义肢。功能评分平均为 57%。通过仔细的患者选择,后肢截肢的肿瘤学结果和功能结果证明其继续使用是合理的。