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术中使用枸橼酸盐敷料收集失血用于自体输血。一项在猪身上的实验研究。

Intraoperative collection of shed blood with citrated compresses for autotransfusion. An experimental study in pigs.

作者信息

Vagianos C, Steen S, Johansson S, Masson P, Tengborn L, Solem J O

机构信息

Department of Cardiothoracic Surgery, University of Lund, Sweden.

出版信息

Acta Chir Scand. 1990 Feb;156(2):121-6.

PMID:2330790
Abstract

Six pigs were used to study whether the collection of shed blood by means of surgical compresses instead of suction traumatizes such blood. In an in vivo part of the study, the whole blood volume of the pigs was retransfused after treatment with citrated compresses, and in an in vitro part the blood was treated extensively with compresses and analyzed. All animals survived, with a minor fall in hemoglobin after 48 hours and a rise in serum citrate concentration at the end of the experiment. A study of the coagulation system revealed no important change after retransfusion of compress-treated blood. In the in vitro part of the study, repeatedly squeezing blood from the compresses increased the concentration of free hemoglobin to a maximum of 5 g/l after ten squeezes, whereas platelets were numerically unchanged. The study indicates that collecting shed blood by means of surgical compresses may be a safe and efficient method.

摘要

六头猪被用于研究通过手术压迫而非抽吸来收集流出的血液是否会对这种血液造成损伤。在该研究的体内部分,用枸橼酸盐压迫处理后,将猪的全血进行回输,而在体外部分,血液用压迫物进行广泛处理并分析。所有动物均存活,48小时后血红蛋白略有下降,实验结束时血清枸橼酸盐浓度升高。对凝血系统的研究表明,回输经压迫处理的血液后没有重要变化。在该研究的体外部分,反复从压迫物中挤压出血液,十次挤压后游离血红蛋白浓度最高增加到5 g/l,而血小板数量未变。该研究表明,通过手术压迫收集流出的血液可能是一种安全有效的方法。

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Acta Chir Scand. 1990 Feb;156(2):121-6.
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