O'Connor D W, Pollitt P A, Hyde J B, Fellows J L, Miller N D, Roth M
Hughes Hall, Cambridge, United Kingdom.
Acta Psychiatr Scand. 1990 Jan;81(1):78-82. doi: 10.1111/j.1600-0447.1990.tb06453.x.
Elderly Cambridge residents diagnosed as demented using the Cambridge Mental Disorders of the Elderly Examination (CAMDEX) were reviewed approximately 12 months later. Diagnoses were confirmed in 133 of 137 surviving cases (97%). Subjects said to have minimal dementia (cognitive impairment insufficient to warrant a diagnosis of dementia proper) had a varied outcome. Only 6 out of 29 survivors showed progressive intellectual deterioration and 13 were reclassified as normal. Subjects passed as normal in the first year of the study were reviewed using the Mini-Mental State Examination. We cannot be certain how many were actually dementing, but our findings suggest that only a small number of false negative diagnoses were made in the first year of the study.
使用《剑桥老年精神障碍检查表》(CAMDEX)被诊断为痴呆的剑桥老年居民在大约12个月后接受了复查。137例存活病例中有133例(97%)确诊。被认为患有轻度痴呆(认知障碍程度不足以确诊为真性痴呆)的受试者有不同的转归。29名存活者中只有6人出现进行性智力衰退,13人被重新归类为正常。在研究的第一年被判定为正常的受试者使用简易精神状态检查表进行了复查。我们无法确定实际有多少人正在发展为痴呆,但我们的研究结果表明,在研究的第一年只有少数假阴性诊断。