Fulton J E, Briles R W, Lamont S J
Department of Animal Science and Immunobiology Program, Iowa State University, Ames 50011.
Anim Genet. 1990;21(1):39-45. doi: 10.1111/j.1365-2052.1990.tb03205.x.
A monoclonal antibody (ISU-cA) was produced that recognized certain alloantigens of the chicken A blood group locus. Antigens produced by alleles A3, A4 and A8 were positive, and those produced by A2 and A5 were negative, by haemagglutination. The specificity of ISU-cA for chicken A blood group antigens was demonstrated by serologic analyses, genetic crosses and competitive inhibition of binding by anti-A alloantisera. To our knowledge, this is the first reported monoclonal antibody against a chicken blood group alloantigen system other than the B complex.
