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[Not Available].[无可用内容]
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本文引用的文献

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High rates of obesity and non-communicable diseases predicted across Latin America.预计拉丁美洲肥胖率和非传染性疾病发病率居高不下。
PLoS One. 2012;7(8):e39589. doi: 10.1371/journal.pone.0039589. Epub 2012 Aug 13.
2
Global nutrition transition and the pandemic of obesity in developing countries.全球营养转型与发展中国家肥胖症流行。
Nutr Rev. 2012 Jan;70(1):3-21. doi: 10.1111/j.1753-4887.2011.00456.x.
3
Hypertension in obesity.肥胖与高血压。
Med Clin North Am. 2011 Sep;95(5):903-17. doi: 10.1016/j.mcna.2011.06.004.
4
Obesity and the orthopedic trauma patient: a review of the risks and challenges in medical and surgical management.肥胖与骨科创伤患者:医学及手术治疗中的风险与挑战综述
Hosp Pract (1995). 2011 Feb;39(1):146-52. doi: 10.3810/hp.2011.02.385.
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Perioperative myocardial ischemia and isolated systolic hypertension in non-cardiac surgery.非心脏手术中的围手术期心肌缺血和孤立性收缩期高血压。
Can J Anaesth. 2011 May;58(5):428-35. doi: 10.1007/s12630-011-9477-7. Epub 2011 Feb 24.
6
Perioperative stroke after total joint arthroplasty: prevalence, predictors, and outcome.全关节置换术后围手术期卒中:发生率、预测因素和结局。
J Bone Joint Surg Am. 2010 Sep 1;92(11):2095-101. doi: 10.2106/JBJS.I.00940.
7
Intraoperative systolic blood pressure variability predicts 30-day mortality in aortocoronary bypass surgery patients.主动脉冠状动脉旁路移植术患者术中收缩压变异性预测 30 天死亡率。
Anesthesiology. 2010 Aug;113(2):305-12. doi: 10.1097/ALN.0b013e3181e07ee9.
8
Primary care survey of awareness and control of hypertension: a hospital-based study.高血压知晓率和控制率的基层医疗调查:一项基于医院的研究。
Am J Ther. 2010 May-Jun;17(3):295-300. doi: 10.1097/MJT.0b013e3181bdc3f6.
9
Perioperative acute ischemic stroke in noncardiac and nonvascular surgery: incidence, risk factors, and outcomes.非心脏和非血管手术中的围手术期急性缺血性卒中:发病率、危险因素及预后
Anesthesiology. 2009 Feb;110(2):231-8. doi: 10.1097/ALN.0b013e318194b5ff.
10
Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.研究电子数据采集(REDCap)——一种用于提供转化研究信息学支持的元数据驱动方法和工作流程。
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肥胖症和高血压是全关节置换术中血流动力学控制不佳的决定因素:一项回顾性研究。

Obesity & hypertension are determinants of poor hemodynamic control during total joint arthroplasty: a retrospective review.

机构信息

Harvard Medical School, Boston, MA 02115, USA.

出版信息

BMC Musculoskelet Disord. 2013 Jan 14;14:20. doi: 10.1186/1471-2474-14-20.

DOI:10.1186/1471-2474-14-20
PMID:23311863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3560179/
Abstract

BACKGROUND

Proper blood pressure control during surgical procedures such as total joint arthroplasty (TJA) is considered critical to good outcome. There is poor understanding of the pre-operative risk factors for poor intra-operative hemodynamic control. The purpose of this study is to identify risk factors for poor hemodynamic control during TJA.

METHODS

We performed a retrospective cohort analysis of 118 patients receiving TJA in the Dominican Republic. We collected patient demographic and comorbidity data. We developed an a priori definition for poor hemodynamic control: 1) Mean arterial pressure (MAP) <65% of preoperative MAP or 2) MAP >135% of preoperative MAP. We performed bivariate and multivariate analyses to identify risk factors for poor hemodynamic control during TJA.

RESULTS

Hypertension was relatively common in our study population (76 of 118 patients). Average preoperative mean arterial pressure was 109.0 (corresponding to an average SBP of 149 and DBP of 89). Forty-nine (41.5%) patients had intraoperative blood pressure readings consistent with poor hemodynamic control. Based on multi-variable analysis preoperative hypertension of any type (RR 2.9; 95% CI 1.3-6.3) and an increase in BMI (RR 1.2 per 5 unit increase; 95% CI 1.0-1.5) were significant risk factors for poor hemodynamic control.

CONCLUSIONS

Preoperative hypertension and being overweight/obese increase the likelihood of poor blood pressure control during TJA. Hypertensive and/or obese patients warrant further attention and medical optimization prior to TJA. More work is required to elucidate the relationship between these risk factors and overall outcome.

摘要

背景

在全关节置换术(TJA)等手术过程中,适当的血压控制被认为是良好结果的关键。对于术中血流动力学控制不良的术前危险因素知之甚少。本研究的目的是确定 TJA 术中血流动力学控制不良的危险因素。

方法

我们对多米尼加共和国接受 TJA 的 118 例患者进行了回顾性队列分析。我们收集了患者的人口统计学和合并症数据。我们预先定义了血流动力学控制不良的标准:1)平均动脉压(MAP)<术前 MAP 的 65%或 2)MAP >术前 MAP 的 135%。我们进行了单变量和多变量分析,以确定 TJA 期间血流动力学控制不良的危险因素。

结果

在我们的研究人群中,高血压相对常见(118 例患者中有 76 例)。平均术前平均动脉压为 109.0(对应平均 SBP 为 149,DBP 为 89)。49 例(41.5%)患者术中血压读数符合血流动力学控制不良。基于多变量分析,术前任何类型的高血压(RR 2.9;95%CI 1.3-6.3)和 BMI 增加(RR 每增加 5 个单位增加 1.2;95%CI 1.0-1.5)是血流动力学控制不良的显著危险因素。

结论

术前高血压和超重/肥胖增加了 TJA 期间血压控制不良的可能性。高血压和/或肥胖患者在接受 TJA 前需要进一步关注和医学优化。需要进一步研究这些危险因素与总体结果之间的关系。