Harvard Medical School, Boston, MA 02115, USA.
BMC Musculoskelet Disord. 2013 Jan 14;14:20. doi: 10.1186/1471-2474-14-20.
Proper blood pressure control during surgical procedures such as total joint arthroplasty (TJA) is considered critical to good outcome. There is poor understanding of the pre-operative risk factors for poor intra-operative hemodynamic control. The purpose of this study is to identify risk factors for poor hemodynamic control during TJA.
We performed a retrospective cohort analysis of 118 patients receiving TJA in the Dominican Republic. We collected patient demographic and comorbidity data. We developed an a priori definition for poor hemodynamic control: 1) Mean arterial pressure (MAP) <65% of preoperative MAP or 2) MAP >135% of preoperative MAP. We performed bivariate and multivariate analyses to identify risk factors for poor hemodynamic control during TJA.
Hypertension was relatively common in our study population (76 of 118 patients). Average preoperative mean arterial pressure was 109.0 (corresponding to an average SBP of 149 and DBP of 89). Forty-nine (41.5%) patients had intraoperative blood pressure readings consistent with poor hemodynamic control. Based on multi-variable analysis preoperative hypertension of any type (RR 2.9; 95% CI 1.3-6.3) and an increase in BMI (RR 1.2 per 5 unit increase; 95% CI 1.0-1.5) were significant risk factors for poor hemodynamic control.
Preoperative hypertension and being overweight/obese increase the likelihood of poor blood pressure control during TJA. Hypertensive and/or obese patients warrant further attention and medical optimization prior to TJA. More work is required to elucidate the relationship between these risk factors and overall outcome.
在全关节置换术(TJA)等手术过程中,适当的血压控制被认为是良好结果的关键。对于术中血流动力学控制不良的术前危险因素知之甚少。本研究的目的是确定 TJA 术中血流动力学控制不良的危险因素。
我们对多米尼加共和国接受 TJA 的 118 例患者进行了回顾性队列分析。我们收集了患者的人口统计学和合并症数据。我们预先定义了血流动力学控制不良的标准:1)平均动脉压(MAP)<术前 MAP 的 65%或 2)MAP >术前 MAP 的 135%。我们进行了单变量和多变量分析,以确定 TJA 期间血流动力学控制不良的危险因素。
在我们的研究人群中,高血压相对常见(118 例患者中有 76 例)。平均术前平均动脉压为 109.0(对应平均 SBP 为 149,DBP 为 89)。49 例(41.5%)患者术中血压读数符合血流动力学控制不良。基于多变量分析,术前任何类型的高血压(RR 2.9;95%CI 1.3-6.3)和 BMI 增加(RR 每增加 5 个单位增加 1.2;95%CI 1.0-1.5)是血流动力学控制不良的显著危险因素。
术前高血压和超重/肥胖增加了 TJA 期间血压控制不良的可能性。高血压和/或肥胖患者在接受 TJA 前需要进一步关注和医学优化。需要进一步研究这些危险因素与总体结果之间的关系。