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肥胖患者下肢关节置换术后行减重手术可改善结局:纽约州全州数据库的倾向评分匹配分析。

Bariatric Surgery Improves Outcomes After Lower Extremity Arthroplasty in the Morbidly Obese: A Propensity Score-Matched Analysis of a New York Statewide Database.

机构信息

Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, New York.

Department of Epidemiology and Biostatistics, Hospital for Special Surgery, New York, New York.

出版信息

J Arthroplasty. 2018 Jul;33(7):2062-2069.e4. doi: 10.1016/j.arth.2017.11.056. Epub 2017 Dec 5.

DOI:10.1016/j.arth.2017.11.056
PMID:29366728
Abstract

BACKGROUND

The purpose of this study was to compare risks for revision and short-term complications after total joint arthroplasty (TJA) in matched cohorts of morbidly obese patients, receiving and not receiving prior bariatric surgery.

METHODS

Patients undergoing elective TJA between 1997 and 2011 were identified in a New York Statewide database, analyzing total knee arthroplasty (TKA) and total hip arthroplasty (THA) separately. Propensity scores were used to match morbidly obese patients receiving and not receiving bariatric surgery prior to TJA. Cox proportional hazard modeling assessed revision risk. Logistic regression evaluated odds for complications.

RESULTS

For TKA, 2636 bariatric surgery patients were matched to 2636 morbidly obese patients. For THA, 792 bariatric surgery patients were matched to 792 morbidly obese patients. Matching balanced all covariates. Bariatric surgery reduced co-morbidities prior to TJA (TKA P < .0001; THA P < .005). Risks for in-hospital complications were lower for THA and TKA patients receiving prior bariatric surgery (odds ratio [OR] 0.25, P < .001; and OR = 0.69, P = .021, respectively). Risks for 90-day complications were lower for TKA (OR 0.61, P = .002). Revision risks were not different for either THA (P = .634) or TKA (P = .431), nor was THA dislocation risk (P = 1.000).

CONCLUSION

After accounting for relevant selection biases, bariatric surgery prior to TJA was associated with reduced co-morbidity burden at the time of TJA and with reduced post-TJA complications. However, bariatric surgery did not reduce the risk for revision surgery for either TKA or THA.

摘要

背景

本研究旨在比较接受和未接受减重手术的病态肥胖患者在接受全关节置换术(TJA)后的翻修风险和短期并发症。

方法

在纽约州范围内的数据库中确定了 1997 年至 2011 年间接受择期 TJA 的患者,分别分析全膝关节置换术(TKA)和全髋关节置换术(THA)。使用倾向评分匹配接受和未接受 TJA 前减重手术的病态肥胖患者。Cox 比例风险模型评估了翻修风险。Logistic 回归评估了并发症的可能性。

结果

对于 TKA,2636 例接受减重手术的患者与 2636 例病态肥胖患者相匹配。对于 THA,792 例接受减重手术的患者与 792 例病态肥胖患者相匹配。匹配平衡了所有协变量。TJA 前减重手术降低了合并症(TKA P<0.0001;THA P<0.005)。接受减重手术的 THA 和 TKA 患者的院内并发症风险较低(比值比 [OR] 0.25,P<0.001;OR=0.69,P=0.021)。接受减重手术的 TKA 患者的 90 天并发症风险较低(OR 0.61,P=0.002)。THA(P=0.634)或 TKA(P=0.431)的翻修风险无差异,THA 脱位风险也无差异(P=1.000)。

结论

在考虑到相关选择偏差后,TJA 前的减重手术与 TJA 时合并症负担减轻和 TJA 后并发症减少相关。然而,减重手术并没有降低 TKA 或 THA 的翻修手术风险。

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