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早产儿和足月儿的神经行为发育:生物医学和环境影响。

Neurobehavioral development of preterm and full term children: biomedical and environmental influences.

机构信息

Department of Developmental Psychology, University of Santiago de Compostela, Spain.

出版信息

Early Hum Dev. 2013 Jun;89(6):401-9. doi: 10.1016/j.earlhumdev.2012.12.008. Epub 2013 Jan 9.

Abstract

BACKGROUND

Previous studies indicate that VLBW preterm children obtain significantly lower scores than full-term children in all the NBAS clusters. However the samples studied usually presented additional medical complications.

AIMS

The present study aims to compare the results obtained by low-risk preterm and full term children in the NBAS, and relate possible differences to biological and contextual factors.

METHOD

Early neurobehavioral development of 150 preterm (PR) children is compared to that of 49 full term children (FT). The children were assessed at the age of 15 days (corrected age for preterm children) with the NBAS. Biological and environmental variables were collected through an extended interview with the mothers as well as medical data.

RESULTS

Significant differences were found between preterm and full term children in the following areas: motor, range of state, and regulation of state. Differences were also found in relation to birth weight in these same three areas, following a parallel pattern. These differences between the two groups were not, however, necessarily more favorable for the FT group; the PR group had higher results in the motor and range of state areas, and lower results in the regulation of state area. The mothers' smoking habit had a negative effect on infants' regulation and orientation.

CONCLUSIONS

No general maturation delay in this particular sample of preterm children was found.

摘要

背景

先前的研究表明,VLBW 早产儿在所有 NBAS 群集中的得分明显低于足月产儿。然而,研究的样本通常存在额外的医疗并发症。

目的

本研究旨在比较低危早产儿和足月产儿在 NBAS 中获得的结果,并将可能的差异与生物学和环境因素联系起来。

方法

将 150 名早产儿(PR)和 49 名足月产儿(FT)的早期神经行为发育进行比较。这些儿童在出生后 15 天(早产儿的矫正年龄)用 NBAS 进行评估。通过对母亲进行扩展访谈以及收集医疗数据来收集生物学和环境变量。

结果

在运动、状态范围和状态调节方面,早产儿和足月产儿之间存在显著差异。在这三个领域,与出生体重相关的差异也呈现出类似的模式。然而,这两组之间的差异并不一定对 FT 组更有利;PR 组在运动和状态范围方面的得分较高,而在状态调节方面的得分较低。母亲的吸烟习惯对婴儿的调节和定向有负面影响。

结论

在这个特定的早产儿样本中,没有发现普遍的成熟延迟。

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