Department of Surgery/Emergency Medicine, Stanford University, , Stanford, California, USA.
Emerg Med J. 2014 Feb;31(2):96-100. doi: 10.1136/emermed-2012-202143. Epub 2013 Jan 12.
To determine risk factors associated with infection and traumatic lacerations and to see if a relationship exists between infection and time to wound closure after injury.
Consecutive patients presenting with traumatic lacerations at three diverse emergency departments were prospectively enrolled and 27 variables were collected at the time of treatment. Patients were followed for 30 days to determine the development of a wound infection and desire for scar revision.
2663 patients completed follow-up and 69 (2.6%, 95% CI 2.0% to 3.3%) developed infection. Infected wounds were more likely to receive a worse cosmetic rating and more likely to be considered for scar revision (RR 2.6, 95% CI 1.7 to 3.9). People with diabetes (RR 2.70, 95% CI 1.1 to 6.5), lower extremity lacerations (RR 4.1, 95% CI 2.5 to 6.8), contaminated lacerations (RR 2.0, 95% CI 1.2 to 3.4) and lacerations greater than 5 cm (RR 2.9, 95% CI 1.6 to 5.2) were more likely to develop an infection. There were no differences in the infection rates for lacerations closed before 3% (95% CI 2.3% to 3.8%) or after 1.2% (95% CI 0.03% to 6.4%) 12 h.
Diabetes, wound contamination, length greater than 5 cm and location on the lower extremity are important risk factors for wound infection. Time from injury to wound closure is not as important as previously thought. Improvements in irrigation and decontamination over the past 30 years may have led to this change in outcome.
确定与感染和创伤性撕裂伤相关的危险因素,并观察创伤后伤口闭合时间与感染之间是否存在关系。
前瞻性纳入在 3 个不同急诊部门就诊的创伤性撕裂伤患者,并在治疗时收集 27 个变量。对患者进行 30 天随访,以确定是否发生伤口感染和是否需要瘢痕修复。
2663 例患者完成了随访,69 例(2.6%,95%CI 2.0%至 3.3%)发生感染。感染伤口更可能获得较差的美容评分,更可能需要瘢痕修复(RR 2.6,95%CI 1.7 至 3.9)。患有糖尿病(RR 2.70,95%CI 1.1 至 6.5)、下肢撕裂伤(RR 4.1,95%CI 2.5 至 6.8)、污染性撕裂伤(RR 2.0,95%CI 1.2 至 3.4)和长度大于 5cm 的撕裂伤(RR 2.9,95%CI 1.6 至 5.2)的患者更有可能发生感染。在伤后 3%(95%CI 2.3%至 3.8%)或 12 小时后 1.2%(95%CI 0.03%至 6.4%)内闭合伤口的感染率没有差异。
糖尿病、伤口污染、长度大于 5cm 和下肢位置是伤口感染的重要危险因素。从受伤到伤口闭合的时间并不像以前认为的那么重要。过去 30 年来冲洗和去污方面的改进可能导致了这一结果的改变。