Medicine Service and Center for Surgical Medical Acute care Research and Transitions (C-SMART), Birmingham VA Medical Center, Birmingham, AL 35294, USA.
Curr Rheumatol Rep. 2013 Feb;15(2):307. doi: 10.1007/s11926-012-0307-x.
Gout affects 8.3 million Americans according to NHANES 2007-2008, approximately 3.9 % of the US population. Gout has substantial effect on physical function, productivity, health-related quality of life (HRQOL), and health care costs. Uncontrolled gout is also associated with significant use of emergency care services. Women are less likely to have gout than men, but in the postmenopausal years the gender difference in disease incidence decreases. Compared with whites, racial and/or ethnic minorities, especially blacks, have higher prevalence of gout. Blacks are also less likely to receive quality gout care, leading to disproportionate morbidity. Women are less likely than men to receive allopurinol, and less likely to undergo joint aspirations for crystal analysis to establish diagnosis, but those on urate-lowering therapy are as likely as, or more likely than, men to undergo serum urate check within six months of initiation. Although a few studies provide the knowledge related to gender and race and/or ethnicity disparities for gout, several knowledge gaps exist in gout epidemiology and outcomes differences by gender and race and/or ethnicity. These should be investigated in future studies.
根据 2007-2008 年 NHANES 调查,美国有 830 万人患有痛风,约占美国总人口的 3.9%。痛风对身体功能、生产力、健康相关生活质量(HRQOL)和医疗保健费用都有重大影响。未经控制的痛风也与大量使用急诊护理服务有关。女性患痛风的可能性低于男性,但在绝经后,疾病发病率的性别差异会减小。与白人相比,少数族裔(尤其是黑人)患痛风的比例更高。少数族裔也不太可能获得优质的痛风治疗,导致发病率不成比例。女性接受别嘌醇治疗的可能性低于男性,接受关节抽吸以进行晶体分析以确诊的可能性也低于男性,但接受尿酸降低治疗的女性与男性一样,或更有可能在开始治疗后的六个月内进行血尿酸检查。尽管一些研究提供了与痛风的性别和种族/民族差异相关的知识,但在痛风流行病学和性别、种族/民族差异方面的结果方面仍存在一些知识空白。这些问题应该在未来的研究中进行调查。