视网膜神经节细胞重复放电的建模。
Modeling the repetitive firing of retinal ganglion cells.
作者信息
Fohlmeister J F, Coleman P A, Miller R F
机构信息
Department of Physiology, University of Minnesota, Minneapolis 55455.
出版信息
Brain Res. 1990 Mar 5;510(2):343-5. doi: 10.1016/0006-8993(90)91388-w.
PMID:2331606
Abstract
A kinetic model for the repetitive firing of retinal ganglion cells was synthesized from voltage-clamp data and evaluated by comparison with whole cell recordings from ganglion cells in the intact tiger salamander retina. Five distinct channels were included in the model and were sufficient to describe the physiologically observed frequency/current relationship in response to various levels of cell depolarization.
摘要
基于电压钳数据构建了视网膜神经节细胞重复放电的动力学模型，并通过与完整虎蝾螈视网膜神经节细胞的全细胞记录进行比较来评估该模型。该模型包含五个不同的通道，足以描述在不同程度的细胞去极化情况下生理上观察到的频率/电流关系。
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