Chedid N R, Bourgeois D, Kaloustian H, Pilipili C, Baba N Z
Dpt Pediatric and Community Dentistry, Fac. Médecine dentaire, Univ. Saint-Joseph, Beirut, Lebanon.
Odontostomatol Trop. 2012 Sep;35(139):26-40.
This clinical prospective study describes how caries preventive measures applied according to caries risk affect new caries incidence in a group of preschoolers, as compared to a group where standardized caries prevention is applied, regardless of risk.
Healthy children, aged four years or less, recruited at the Faculté de Médecine Dentaire, Université Saint-Joseph, Beirut, Lebanon were assigned, after parental consent, to an experimental or a control group. Caries risk was determined based on a parental questionnaire, salivary levels of Steptococcus mutans (Sm) and Lactobacillus (Lb), salivary buffer capacity, plaque levels and carious lesions prevalence, then subjects were classified into four caries risk categories. In the experimental group, preventive measures designed for each risk category were applied periodically, whereas control subjects received only standardized preventive measures at regular intervals. All subjects were reevaluated for Sm, Lb, salivary buffer capacity, plaque and new carious lesions after 24 months.
Statistically significant reductions in salivary Sm (p=0.001) and Lb (p=0.003) levels, plaque scores (p=0) and caries incidence (p=0.003) were observed in the experimental group. In the control group, no significant differences were observed between initial and final Sm (p=0.18) and Lb (p=0.109) levels or plaque scores (p=0.255), and caries incidence was not significantly reduced (p=0.584).
The present study's results suggest that caries preventive measures applied according to caries risk may reduce caries risk factors and new caries incidence in preschool-aged children. These findings deserve further investigation to benefit early childhood caries prevention on a larger scale.
本临床前瞻性研究描述了根据龋齿风险采取的预防措施对一组学龄前儿童新发龋齿发生率的影响,并与一组采取标准化龋齿预防措施(无论风险如何)的儿童进行比较。
在黎巴嫩贝鲁特圣约瑟夫大学牙科学院招募的4岁及以下健康儿童,经家长同意后,被分配到实验组或对照组。根据家长问卷、变形链球菌(Sm)和乳酸杆菌(Lb)的唾液水平、唾液缓冲能力、牙菌斑水平和龋齿病变患病率确定龋齿风险,然后将受试者分为四个龋齿风险类别。在实验组中,针对每个风险类别设计的预防措施定期应用,而对照组受试者仅定期接受标准化预防措施。24个月后,对所有受试者的Sm、Lb、唾液缓冲能力、牙菌斑和新发龋齿病变进行重新评估。
实验组唾液Sm水平(p = 0.001)、Lb水平(p = 0.003)、牙菌斑评分(p = 0)和龋齿发生率(p = 0.003)有统计学意义的降低。在对照组中,初始和最终的Sm水平(p = 0.18)、Lb水平(p = 0.109)或牙菌斑评分(p = 0.255)之间没有显著差异,龋齿发生率也没有显著降低(p = 0.584)。
本研究结果表明,根据龋齿风险采取的预防措施可能会降低学龄前儿童的龋齿风险因素和新发龋齿发生率。这些发现值得进一步研究,以在更大范围内促进幼儿龋齿预防。