Levi Assi, Ingber Arieh, Enk David Claes
Department of Dermatology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Harefuah. 2012 Oct;151(10):576-80, 605.
Reflectance-mode confocal scanning laser microscopy is a novel, non-invasive imaging technique which permits real time visualization of cellular components in the skin at a resolution close to that of conventional histology. It has been widely used in the diagnosis of both benign and malignant tumors of the skin. In recent years it was also employed in the investigation of a variety of inflammatory and infectious skin conditions. The non-invasive nature of the procedure allows examination of multiple lesions and/ or repetitive sampling of one lesion over time, making it an excellent tool for followup and for monitoring treatment outcome in medical and cosmetic dermatology. This review summarizes the main indications for the use of this novel technique in clinical and experimental dermatology.
反射模式共聚焦扫描激光显微镜是一种新型的非侵入性成像技术，它能够以接近传统组织学的分辨率实时观察皮肤中的细胞成分。它已被广泛应用于皮肤良恶性肿瘤的诊断。近年来，它还被用于研究各种炎症性和感染性皮肤病。该检查的非侵入性特点允许对多个皮损进行检查和/或对一个皮损进行随时间的重复取样，使其成为医学和美容皮肤病学中随访及监测治疗效果的极佳工具。这篇综述总结了这项新技术在临床和实验皮肤病学中的主要应用指征。
