Ludwig-Maximilian University of Munich, Department of Dermatology and Allergology, Germany.
J Biomed Opt. 2013 Jun;18(6):061224. doi: 10.1117/1.JBO.18.6.061224.
Optical coherence tomography (OCT) is a noninvasive diagnostic method that offers a view into the superficial layers of the skin in vivo in real-time. An infrared broadband light source allows the investigation of skin architecture and changes up to a depth of 1 to 2 mm with a resolution between 15 and 3 μm, depending on the system used. Thus OCT enables evaluation of skin lesions, especially nonmelanoma skin cancers and inflammatory diseases, quantification of skin changes, visualization of parasitic infestations, and examination of other indications such as the investigation of nails. OCT provides a quick and useful diagnostic imaging technique for a number of clinical questions and is a valuable addition or complement to other noninvasive imaging tools such as dermoscopy, high-frequency ultrasound, and confocal laser scan microscopy.
光学相干断层扫描（OCT）是一种非侵入性诊断方法，可实时提供体内皮肤浅层的视图。红外宽带光源允许用分辨率在 15 至 3 微米之间（取决于所用的系统）对皮肤结构和变化进行 1 至 2 毫米深度的探测。因此，OCT 可用于评估皮肤病变，特别是非黑色素瘤皮肤癌和炎症性疾病，量化皮肤变化，可视化寄生虫感染，并检查其他适应症，如指甲检查。OCT 为许多临床问题提供了一种快速有用的诊断成像技术，是皮肤镜、高频超声和共聚焦激光扫描显微镜等其他非侵入性成像工具的有益补充。
