Vian Izabele, Zielinsky Paulo, Zilio Ana Maria, Mello Anne, Lazzeri Bruna, Oliveira Andressa, Lampert Kenya Venusa, Piccoli Antônio, Nicoloso Luis Henrique, Bubols Guilherme Borges, Garcia Solange Cristina
Fetal Cardiology Unit, Institute of Cardiology of Estado do Rio Grande do Sul, Porto Alegre, Brazil.
Departament of Toxicology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Matern Child Nutr. 2015 Oct;11(4):511-24. doi: 10.1111/mcn.12025. Epub 2013 Jan 15.
Previous studies have shown that maternal consumption of polyphenol-rich foods after the third trimester of pregnancy may interfere with the anatomical and functional activity of the fetal heart as, to our knowledge, there are no validated instruments to quantify total polyphenols in pregnant women. The aim of this study was evaluate the reproducibility and validity of a food frequency questionnaire (FFQ), with 52 items, to assess the intake of polyphenol-rich foods in pregnant women in Brazil. This cross-sectional study included 120 pregnant women who participated in nutritional interviews in two moments. The intake of polyphenols estimated by the developed FFQ was compared with the average of two 24-h recalls (24HR), with the average intake measured by a 3-day food diary (D3days) and with the urinary excretion of total polyphenols. The triangular method was applied to calculate Pearson's correlation coefficients, intraclass correlation and Bland-Altman plots for the FFQ, using an independent biochemical marker, in addition to classification by quarters of consumption. The questionnaires were log transformed, adjusted for body mass index and gestational age. The adjustment for energy was applied only of 24HR and D3days. Analysis of the reproducibility between the FFQ showed a very high correlation (r = 0.72; P < 0.05). A low but significant association was observed between the FFQ and urinary excretion (0.23; P = 0.01). The association between the dietary survey methods was moderate to very high (r = 0.36 to r = 0.72; P < 0.001). In conclusion, this questionnaire showed reproducibility and validity for the quantification of consumption of total polyphenols in pregnant women.
先前的研究表明，妊娠晚期孕妇食用富含多酚的食物可能会干扰胎儿心脏的解剖结构和功能活动，因为据我们所知，尚无经过验证的工具可量化孕妇体内的总多酚含量。本研究的目的是评估一份包含52个条目的食物频率问卷（FFQ）在评估巴西孕妇富含多酚食物摄入量方面的可重复性和有效性。这项横断面研究纳入了120名孕妇，她们分两个阶段参与了营养访谈。将所开发的FFQ估算的多酚摄入量与两次24小时膳食回顾（24HR）的平均值、3天食物日记（D3days）测量的平均摄入量以及总多酚的尿排泄量进行比较。除了按消费四分位数进行分类外，还应用三角法计算FFQ的Pearson相关系数、组内相关系数和Bland-Altman图，并使用独立的生化标志物。问卷进行对数转换，根据体重指数和孕周进行调整。仅对24HR和D3days进行能量调整。FFQ之间的可重复性分析显示出非常高的相关性（r = 0.72；P < 0.05）。FFQ与尿排泄之间观察到低但显著的关联（0.23；P = 0.01）。膳食调查方法之间的关联为中度至非常高（r = 0.36至r = 0.72；P < 0.001）。总之，这份问卷在量化孕妇总多酚摄入量方面显示出可重复性和有效性。
