Norouzinia M, Asadzadeh H, Shalmani H Mohaghegh, Al Dulaimi D, Zali M R
Research Institute for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Science, Tehran, Iran.
Asian Pac J Cancer Prev. 2012;13(11):5677-9. doi: 10.7314/apjcp.2012.13.11.5677.
Gastric cancer is the second most common cancer worldwide. In this study the clinical and histological features of gastric cancer in the cardia and distal stomach were evaluated.
Proximal and distal gastric cancer diagnosed and treated in eight provinces of Iran from 2010-2011 were reviewed in all collected cases. The age standardized incident rates were calculated and tumor location and histological type were recorded.
The age-standardized incidence rate for the eight centers was 40.6 per 100,000 populations per year with an upper and lower range of 22.1 and 102.4 per 100,000 population per year. Thirty four percent of the tumors were located in the cardia, 3% in fundus, and 63% in the distal stomach. In 7 provinces the prevalence of distal tumors was significantly greater than proximal tumors (p=0.006). A significant relationship was observed between diffuse form of gastric cancer and distal gastric tumors (p=0.007) and between poor tumor differentiation and distal gastric tumors (p<0.001).
the result of this study shows that distal gastric cancer is more common than proximal gastric cancer in Iran.
胃癌是全球第二大常见癌症。本研究对贲门部和胃远端的胃癌临床及组织学特征进行了评估。
回顾了2010年至2011年在伊朗八个省份诊断和治疗的近端和远端胃癌病例。计算年龄标准化发病率，并记录肿瘤位置和组织学类型。
八个中心的年龄标准化发病率为每年每10万人口40.6例，每年每10万人口的上下限分别为22.1例和102.4例。34%的肿瘤位于贲门部，3%位于胃底，63%位于胃远端。在7个省份，远端肿瘤的患病率显著高于近端肿瘤（p = 0.006）。观察到弥漫型胃癌与远端胃肿瘤之间存在显著关系（p = 0.007），以及肿瘤低分化与远端胃肿瘤之间存在显著关系（p < 0.001）。
本研究结果表明，在伊朗，远端胃癌比近端胃癌更常见。
