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[1988年波希米亚地区结核病的流行病学情况及结核病监测的有效性]

[The epidemiologic situation regarding tuberculosis and the effectiveness of tuberculosis surveillance in Bohemia in 1988].

作者信息

Trnka L, Danková D

机构信息

Výzkumný ústav tuberkulózy a respiracních nemocí, Praha.

出版信息

Cas Lek Cesk. 1990 Feb 9;129(6):166-71.

PMID:2331732
Abstract

In the CSR (10 million inhabitants) in 1988 the system of TB surveillance was completed which comprises the national TB programme, the central TB register and the evaluation TB unit. The incidence of respiratory TB in 1988 in the CSR was 15.5/100,000 population. In 71% of the patients the disease was confirmed by bacteriological examination (11.0/100,000 population). The incidence of extrapulmonary TB was 4.2/100,000 population. As compared with previous years, the number of patients declined except patients with already microscopically confirmed acid resistant rods in the sputum; their incidence, 5.5/100,000, remained the same in the CSR since 1986. In this incidence participated in particular middle-aged men. The prevalence of active TB of the respiratory system was 20.0/100,000 population. It was only 1.3 times higher than the incidence, because treatment of TB patients was successful and principles of dispensarization were respected. The number of deaths from TB was 98 (0.9/100,000). In 84 the diagnosis was established only during autopsy. The lethality was high in old people. The course of treatment was evaluated after one year in 1330 patients with respiratory TB diagnosed in 1987. Satisfactory therapeutic results were achieved in 98% of the patients. In the remaining (17) patients bacteriological negativization of the sputum did not occur due to complications of treatment or lack of patient cooperation. 70% of the patients had a therapeutic regime with rifampicin. In-patient treatment was emphasized; the total mean period of administration of antituberculotics was 9.3 months.

摘要

1988年在某社会主义共和国(CSR,1000万人口)建立了结核病监测系统,该系统包括国家结核病规划、中央结核病登记册和结核病评估单位。1988年该社会主义共和国呼吸系统结核病发病率为15.5/10万人口。71%的患者通过细菌学检查确诊(11.0/10万人口)。肺外结核病发病率为4.2/10万人口。与前几年相比,患者人数有所下降,但痰中已显微镜确诊为抗酸杆菌的患者除外;自1986年以来,他们在该社会主义共和国的发病率为5.5/10万,保持不变。在这一发病率中,中年男性占比尤其高。呼吸系统活动性结核病患病率为20.0/10万人口。仅比发病率高1.3倍,因为结核病患者的治疗取得了成功,并且遵循了分级诊疗原则。结核病死亡人数为98人(0.9/10万)。其中84例仅在尸检时才确诊。老年人的致死率很高。对1987年诊断的1330例呼吸系统结核病患者在治疗一年后进行了治疗过程评估。98%的患者取得了满意的治疗效果。其余17例患者由于治疗并发症或患者缺乏合作,痰未实现细菌学转阴。70%的患者采用含利福平的治疗方案。强调住院治疗;抗结核药物的总平均给药期为9.3个月。

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