Lawrence G, Walker P D, Freestone D S, Shann F
P N G Med J. 1979 Mar;22(1):30-4.
In many Highlands hospitals pig-bel is the commonest cause of death in children over 12 months of age. In a double blind controlled trial in Sina Sina we have shown that Clostridium welchii type C beta toxoid (beta toxoid) protects against pig-bel (p < 0.02). Of 2,538 children given beta toxoid, two developed pig-bel in the following two years. Seventeen of 2,532 control children vaccinated with tetanus toxoid developed pig-bel. We suggest that beta toxoid be given to Highlands children at two, four and six months of age. Boosters may be needed. Health services in the Highlands need to be improved so that this vaccine can be effectively delivered.
在许多高地医院,猪瘟是12个月以上儿童最常见的死因。在西纳西纳进行的一项双盲对照试验中,我们已经表明,C型韦氏梭菌β类毒素(β类毒素)可预防猪瘟(p<0.02)。在2538名接种β类毒素的儿童中,有两名在接下来的两年内患上了猪瘟。在2532名接种破伤风类毒素的对照儿童中,有17名患上了猪瘟。我们建议在高地地区,给2个月、4个月和6个月大的儿童接种β类毒素。可能需要加强免疫。高地地区的卫生服务需要改善,以便能有效接种这种疫苗。