通过主动免疫预防巴布亚新几内亚的坏死性小肠结肠炎。
Prevention of necrotising enteritis in Papua New Guinea by active immunisation.
作者信息
Lawrence G, Shann F, Freestone D S, Walker P D
出版信息
Lancet. 1979 Feb 3;1(8110):227-30. doi: 10.1016/s0140-6736(79)90764-5.
PMID:84895
Abstract
Necrotising enteritis (pig-bel) caused by Clostridium welchii type C is a major cause of illness and death in the Highlands of Papua New Guinea. In a controlled trial of active immunisation with a clostridial toxoid prepared from type-C cultures the incidence of pig-bel in over 2500 immunised children within 24 months of immunisation was less than an eighth of that in a control group. Necrotising enteritis in Papua New Guinea is now a preventable disease.
摘要
由C型韦氏梭菌引起的坏死性肠炎（猪霍乱）是巴布亚新几内亚高地疾病和死亡的主要原因。在一项使用由C型培养物制备的梭菌类毒素进行主动免疫的对照试验中，超过2500名免疫儿童在免疫后24个月内猪霍乱的发病率不到对照组的八分之一。巴布亚新几内亚的坏死性肠炎现在是一种可预防的疾病。
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