Dyer J, Wyke S, Lynch C
Royal Liverpool and Broadgreen University Hospitals NHS Trust, UK.
Ann R Coll Surg Engl. 2013 Jan;95(1):65-9. doi: 10.1308/003588413X13511609956219.
Current guidelines on venous thromboembolism (VTE) prevention do not reflect the potential varying risk for patients undergoing different urological procedures. Our study aimed to establish the procedure specific rate of postoperative VTE in patients undergoing urological surgery.
Hospital Episode Statistics were obtained for all patients undergoing common urological procedures between April 2009 and April 2010. This cohort was followed up to identify all patients reattending with either deep vein thrombosis (DVT) or pulmonary embolism (PE) within 12 months.
A total of 126,891 individuals underwent urological surgery during the study period. This included 89,628 men (70.6%) and 37,236 women (29.3%) with a mean age of 65.2 years. At the 12-month follow-up, 839 patients (0.66%) were readmitted with VTE. Of these, 373 (0.29%) were admitted with DVT and 466 (0.37%) with PE. The procedure-specific rate of VTE varied significantly between 2.86% following cystectomy and 0.23% following urethral dilatation. Procedures performed in the lithotomy position carried a significantly lower risk of VTE than those performed in the supine position (0.60% vs 1.28%, p <0.0001). Furthermore, of all procedures performed in the lithotomy position, those performed on benign conditions carried a significantly lower risk than those performed on malignant disease (0.52% vs 0.79%, p <0.0001).
Procedure specific rates of postoperative VTE vary widely among patients undergoing urological procedures. These findings suggest the potential benefit of prolonging the use of thromboprophylaxis in high-risk patients but also exploring the apparent lack of need for routine thromboprophylaxis in patients undergoing low-risk procedures.
当前关于静脉血栓栓塞症(VTE)预防的指南并未反映出接受不同泌尿外科手术的患者潜在的不同风险。我们的研究旨在确定泌尿外科手术患者术后特定手术的VTE发生率。
获取了2009年4月至2010年4月期间接受常见泌尿外科手术的所有患者的医院事件统计数据。对该队列进行随访,以确定在12个月内再次因深静脉血栓形成(DVT)或肺栓塞(PE)就诊的所有患者。
在研究期间,共有126,891人接受了泌尿外科手术。其中包括89,628名男性(70.6%)和37,236名女性(29.3%),平均年龄为65.2岁。在12个月的随访中,839名患者(0.66%)因VTE再次入院。其中,373名(0.29%)因DVT入院,466名(0.37%)因PE入院。VTE的特定手术发生率在膀胱切除术后为2.86%至尿道扩张术后的0.23%之间有显著差异。截石位手术的VTE风险明显低于仰卧位手术(0.60%对1.28%,p<0.0001)。此外,在所有截石位手术中,良性疾病手术的风险明显低于恶性疾病手术(0.52%对0.79%,p<0.0001)。
泌尿外科手术患者术后特定手术的VTE发生率差异很大。这些发现表明,在高危患者中延长使用血栓预防措施可能有益,但也需探讨低风险手术患者明显无需常规血栓预防措施的情况。