Hotel-Dieu de France Hospital, St Joseph University Medical School, Beirut, Lebanon.
JAMA Neurol. 2013 Jan;70(1):114-6. doi: 10.1001/jamaneurol.2013.584.
To highlight the possible association of intracranial aneurysm with autosomal recessive polycystic kidney disease.
DESIGN, SETTING, AND PATIENT: To our knowledge, this association has been reported only twice in the medical literature. We herein report the case of a 21-year-old man with autosomal recessive polycystic kidney disease, presenting with subarachnoid hemorrhage secondary to a ruptured intracranial aneurysm, at our institution.
In the presence of only 3 cases in the medical literature, one might conclude they are a simple coincidence. However, should this association exist, such as with the dominant form, then the neurologic prognosis and even the life of young patients may be at stake.
Given the devastating consequences of intracranial bleeding in young patients, early neurologic screening may be warranted.
强调颅内动脉瘤与常染色体隐性多囊肾病之间可能存在的关联。
设计、地点和患者：据我们所知，这种关联在医学文献中仅报告过两次。我们在此报告了一例在我们机构就诊的 21 岁常染色体隐性多囊肾病男性患者，其因颅内破裂的动脉瘤引起蛛网膜下腔出血。
在文献中只有 3 例病例的情况下，人们可能会认为这只是一个巧合。然而，如果这种关联存在，例如与显性形式一样，那么年轻患者的神经预后甚至生命可能会受到威胁。
鉴于颅内出血对年轻患者的破坏性后果，可能需要进行早期神经筛查。
