狐家庭关系
Fox family ties.
机构信息
Section of Rheumatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
出版信息
Cell Res. 2013 Apr;23(4):452-4. doi: 10.1038/cr.2013.5. Epub 2013 Jan 15.
Abstract
The transcription factor Foxp3 plays an indispensible role in the differentiation of regulatory T (Treg) cells and the expression of their suppressive functions. In a recent article published in Nature, Ouyang et al. demonstrate that Treg cell differentiation is also enabled by transcriptional networks controlled by another Forkhead box family member, Foxo1.
摘要
转录因子 Foxp3 在调节性 T（Treg）细胞的分化和抑制功能的表达中起着不可或缺的作用。在最近发表在《自然》杂志上的一篇文章中，欧阳等人表明，Foxo1 控制的另一个叉头框家族成员转录网络也能使 Treg 细胞分化。
相似文献
1
Fox family ties.狐家庭关系
Cell Res. 2013 Apr;23(4):452-4. doi: 10.1038/cr.2013.5. Epub 2013 Jan 15.
2
Epigenetic and transcriptional control of Foxp3+ regulatory T cells.Foxp3+ 调节性 T 细胞的表观遗传和转录控制。
Semin Immunol. 2015 Feb;27(1):10-8. doi: 10.1016/j.smim.2015.02.002. Epub 2015 Mar 20.
3
From stability to dynamics: understanding molecular mechanisms of regulatory T cells through Foxp3 transcriptional dynamics.从稳定性到动态性：通过 Foxp3 转录动态理解调节性 T 细胞的分子机制。
Clin Exp Immunol. 2019 Jul;197(1):14-23. doi: 10.1111/cei.13194. Epub 2018 Sep 17.
4
Transcriptional regulation of Foxp3 in regulatory T cells.调节性 T 细胞中 Foxp3 的转录调控。
Immunobiology. 2011 Jun;216(6):678-85. doi: 10.1016/j.imbio.2010.11.002. Epub 2010 Nov 13.
5
Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity.调节性T细胞中Foxo1活性的分级可区分肿瘤免疫与自发性自身免疫。
Nature. 2016 Jan 28;529(7587):532-6. doi: 10.1038/nature16486. Epub 2016 Jan 20.
6
Novel Foxo1-dependent transcriptional programs control T(reg) cell function.新型 Foxo1 依赖性转录程序控制 T(reg) 细胞功能。
Nature. 2012 Nov 22;491(7425):554-9. doi: 10.1038/nature11581. Epub 2012 Nov 7.
7
Control of regulatory T-cell differentiation and function by T-cell receptor signalling and Foxp3 transcription factor complexes.调控性 T 细胞分化和功能的 T 细胞受体信号和 Foxp3 转录因子复合物。
Immunology. 2020 May;160(1):24-37. doi: 10.1111/imm.13178. Epub 2020 Mar 9.
8
Molecular mechanisms underlying the regulation and functional plasticity of FOXP3(+) regulatory T cells.FOXP3(+) 调节性 T 细胞调控和功能可塑性的分子机制。
Genes Immun. 2012 Jan;13(1):1-13. doi: 10.1038/gene.2011.77. Epub 2011 Nov 3.
9
Differentiation and function of Foxp3(+) effector regulatory T cells.Foxp3(+)效应性调节 T 细胞的分化与功能。
Trends Immunol. 2013 Feb;34(2):74-80. doi: 10.1016/j.it.2012.11.002. Epub 2012 Dec 6.
10
FoxP3, Helios, and SATB1: roles and relationships in regulatory T cells.FoxP3、Helios 和 SATB1：调节性 T 细胞中的作用和关系。
Int Immunopharmacol. 2013 Jul;16(3):343-7. doi: 10.1016/j.intimp.2013.02.004. Epub 2013 Feb 18.
引用本文的文献
1
Study on the Mechanism of FOXA2 Activation on Glutathione Metabolic Reprogramming Mediated by ETV4 Transcription to Facilitate Colorectal Cancer Malignant Progression.FOXA2通过ETV4转录激活介导的谷胱甘肽代谢重编程促进结直肠癌恶性进展的机制研究
Biochem Genet. 2024 Sep 24. doi: 10.1007/s10528-024-10918-y.
2
Silencing FUT4 Inhibits the Progression of Osteosarcoma through Activation of FOXO1.沉默 FUT4 通过激活 FOXO1 抑制骨肉瘤的进展。
Curr Pharm Des. 2024;30(6):440-447. doi: 10.2174/0113816128269432240103052108.
3
Correlation Between High Expression of FOXA2 and Improved Overall Survival in Ovarian Cancer Patients.FOXA2高表达与卵巢癌患者总生存期改善之间的相关性
Med Sci Monit. 2021 Jan 23;27:e928763. doi: 10.12659/MSM.928763.
本文引用的文献
1
Novel Foxo1-dependent transcriptional programs control T(reg) cell function.新型 Foxo1 依赖性转录程序控制 T(reg) 细胞功能。
Nature. 2012 Nov 22;491(7425):554-9. doi: 10.1038/nature11581. Epub 2012 Nov 7.
2
Regulatory T cells and Foxp3.调节性 T 细胞和 Foxp3。
Immunol Rev. 2011 May;241(1):260-8. doi: 10.1111/j.1600-065X.2011.01018.x.
3
Foxo transcription factors control regulatory T cell development and function.Foxo 转录因子控制调节性 T 细胞的发育和功能。
Immunity. 2010 Dec 14;33(6):890-904. doi: 10.1016/j.immuni.2010.12.002.
4
Foxo: in command of T lymphocyte homeostasis and tolerance.Foxo：T 淋巴细胞稳态和耐受的指挥官。
Trends Immunol. 2011 Jan;32(1):26-33. doi: 10.1016/j.it.2010.10.005. Epub 2010 Nov 23.
5
Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.Foxo 蛋白协同控制 Foxp3+调节性 T 细胞的分化。
Nat Immunol. 2010 Jul;11(7):618-27. doi: 10.1038/ni.1884. Epub 2010 May 13.
6
Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells.转录因子Foxo3通过调节树突状细胞的功能来控制T细胞免疫反应的强度。
Nat Immunol. 2009 May;10(5):504-13. doi: 10.1038/ni.1729. Epub 2009 Apr 12.
7
An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance.叉头框转录因子Foxo1在控制T细胞稳态和耐受性方面的重要作用。
Immunity. 2009 Mar 20;30(3):358-71. doi: 10.1016/j.immuni.2009.02.003. Epub 2009 Mar 12.
8
Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.Foxo1通过调节L-选择素、CCR7和白细胞介素7受体，将初始T细胞的归巢与存活联系起来。
Nat Immunol. 2009 Feb;10(2):176-84. doi: 10.1038/ni.1689. Epub 2009 Jan 11.
9
Regulatory T cell development in the absence of functional Foxp3.在缺乏功能性Foxp3的情况下调节性T细胞的发育
Nat Immunol. 2007 Apr;8(4):359-68. doi: 10.1038/ni1445. Epub 2007 Feb 2.
10
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.发育中和成熟调节性T细胞中Foxp3靶基因的全基因组分析。
Nature. 2007 Feb 22;445(7130):936-40. doi: 10.1038/nature05563. Epub 2007 Jan 21.
Zotero 插件