广州管圆线虫（线虫纲：后圆线虫科）的脂质：成虫与孕虫的比较

Lipids of Angiostrongylus cantonensis (Nematoda: Metastrongyloidea): a comparison between young adults and gravid worms.

Kwong A Y, Wong P C, Ko R C

Department of Biochemistry, University of Hong Kong.

Comp Biochem Physiol B. 1990;95(1):193-7. doi: 10.1016/0305-0491(90)90270-4.

Abstract

All major classes of lipids were found in the young adults in brain (22 days post-infection) and gravid Angiostrongylus cantonensis in lung of rats (34 days post-infection) comprising approximately 60% of phospholipids, 30% of neutral lipids and the rest, glycolipids. 2. The relative composition of phospholipids were quite similar between worms from the two different habitats, with phosphatidylcholine predominating. The glycolipid profiles were also similar. 3. More neutral lipids in the worms from brain existed as cholesterol and cholesterol esters than those from the lung. More than 20% of the fatty acids in these lipids of the brain were found as C10-C14 acids while oleic acid was the main component in the lung worm.

摘要

在感染后22天的大鼠脑中的年轻成虫以及感染后34天的大鼠肺中的广州管圆线虫成虫体内，发现了所有主要类别的脂质，其中磷脂约占60%，中性脂质占30%，其余为糖脂。2. 来自两种不同栖息地的蠕虫中磷脂的相对组成相当相似，以磷脂酰胆碱为主。糖脂谱也相似。3. 脑中蠕虫的中性脂质中胆固醇和胆固醇酯的含量比肺中蠕虫的多。这些脑脂质中超过20%的脂肪酸为C10 - C14酸，而油酸是肺中蠕虫脂质的主要成分。