Schoning P, Hall S M, Hamlet M P
Department of Pathology, College of Veterinary Medicine, Kansas State University, Manhattan 66506.
Cryobiology. 1990 Apr;27(2):189-93. doi: 10.1016/0011-2240(90)90011-r.
Frostbite was produced in the skin of five Hanford Miniature Swine by exposing local areas to chilled air (-75 degrees C) for 1, 3, 5, 10, or 20 min. A copper-constantan thermocouple was inserted into the dermis to measure the temperature. The mean freezing time (the time required to reach 0 degrees C) was approximately 1.9 min. The mean lowest temperatures were 8.8, -15.7, -20.9, -22.5, and -23.4 degrees C for the 1-, 3-, 5-, 10-, and 20-min freezes, respectively. The mean times to rewarm the skin to 25 degrees C were 3.1, 4.5, 5.5, 7.0, and 8.6 min for the 1-, 3-, 5-, 10-, and 20-min freezes, respectively. Significant linear correlations existed between duration of freeze and rewarming times, duration of freeze and lowest temperature, and lowest temperature and rewarming times.
通过将五只汉福德小型猪的局部皮肤暴露于冷空气（-75摄氏度）中1、3、5、10或20分钟，造成冻伤。将铜-康铜热电偶插入真皮以测量温度。平均冻结时间（达到0摄氏度所需的时间）约为1.9分钟。1分钟、3分钟、5分钟、10分钟和20分钟冻结的平均最低温度分别为8.8摄氏度、-15.7摄氏度、-20.9摄氏度、-22.5摄氏度和-23.4摄氏度。1分钟、3分钟、5分钟、10分钟和20分钟冻结的皮肤复温至25摄氏度的平均时间分别为3.1分钟、4.5分钟、5.5分钟、7.0分钟和8.6分钟。冻结持续时间与复温时间、冻结持续时间与最低温度以及最低温度与复温时间之间存在显著的线性相关性。
