Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Nat Rev Clin Oncol. 2013 Feb;10(2):108-16. doi: 10.1038/nrclinonc.2012.237. Epub 2013 Jan 15.
Access to pain relief is a crucial concern for patients with cancer, and remains so at all stages of the illness trajectory. This Review covers the scope of the problem and considers the optimal palliative strategy, mainly through the use of opioids. It also discusses various barriers to effective pain management around the world, including regulatory and attitudinal barriers towards opioids, and the unwillingness of national governments to integrate palliative care effectively in cancer control efforts.
缓解疼痛是癌症患者的关键关注点,在疾病进程的所有阶段都应如此。本综述涵盖了这一问题的范围,并考虑了最佳的姑息治疗策略,主要是通过使用阿片类药物。它还讨论了全球范围内有效疼痛管理的各种障碍,包括对阿片类药物的监管和态度障碍,以及各国政府不愿意在癌症控制工作中有效纳入姑息治疗。