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射频消融治疗放射性直肠炎:病例报告及文献复习。

Radiofrequency ablation for the treatment of radiation proctitis: a case report and review of literature.

机构信息

Seton Hall University, School of Health and Medical Sciences - St. Michael's Medical Center, Department of Medicine, Division of Gastroenterology, 111 Central Avenue, Newark, NJ 07102, USA.

出版信息

Therap Adv Gastroenterol. 2013 Jan;6(1):69-76. doi: 10.1177/1756283X12456895.

DOI:10.1177/1756283X12456895
PMID:23320051
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3539292/
Abstract

Radiation proctitis is a frequent complication of pelvic radiation for cancer. This condition can present acutely within several weeks of radiation, or chronically many months or years after radiation, leading to rectal bleeding and transfusion-dependent anemia. Various medical and endoscopic therapies have been described to treat this condition; however, some patients fail to respond to the current standard therapies. Here we present a case of refractory radiation proctitis, with suboptimal response to other therapies, treated successfully with a novel method, radiofrequency ablation.

摘要

放射性直肠炎是盆腔放射治疗癌症的常见并发症。这种情况可能在放射治疗后数周内急性发作,也可能在放射治疗后数月或数年后慢性发作,导致直肠出血和输血依赖型贫血。已经描述了各种医学和内镜治疗方法来治疗这种情况;然而,一些患者对当前的标准治疗方法没有反应。在这里,我们报告了一例难治性放射性直肠炎的病例,该病例对其他治疗方法反应不佳,成功地采用了一种新的方法,即射频消融术。

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本文引用的文献

1
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World J Gastroenterol. 2011 Nov 7;17(41):4554-62. doi: 10.3748/wjg.v17.i41.4554.
2
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Curr Oncol. 2011 Oct;18(5):220-7. doi: 10.3747/co.v18i5.767.
3
The efficacy of the combination therapy with oral and topical mesalazine for patients with the first episode of radiation proctitis.口服和局部美沙拉嗪联合治疗首发放射性直肠炎患者的疗效。
Dig Dis Sci. 2011 Sep;56(9):2672-7. doi: 10.1007/s10620-011-1637-7. Epub 2011 Mar 2.
4
Treatment of chronic radiation proctitis with cryoablation.冷冻消融治疗慢性放射性直肠炎。
Gastrointest Endosc. 2011 Feb;73(2):383-9. doi: 10.1016/j.gie.2010.10.044.
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Chronic radiation proctitis: issues surrounding delayed bowel dysfunction post-pelvic radiotherapy and an update on medical treatment.慢性放射性直肠炎:盆腔放疗后迟发性肠道功能障碍相关问题及医学治疗更新。
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