从长叶兰中分离得到的新的神经酸衍生物。
New nervogenic acid derivatives from Liparis nervosa.
机构信息
School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, People's Republic of China.
出版信息
Planta Med. 2013 Mar;79(3-4):281-7. doi: 10.1055/s-0032-1328109. Epub 2013 Jan 15.
PMID:23322560
Abstract
Ten new nervogenic acid derivatives (1-4, 6-11) and one known compound (5) have been isolated from Liparis nervosa. Their structures were determined using extensive spectroscopic analysis, including 1D and 2D NMR experiments. Compounds 3, 4, 9, 10, and 11 were evaluated for their cytotoxicity against A549, H460, Hela, MCF-7, Caco2, and HepG2 human cancer cell lines.
摘要
从长距舌唇兰中分离得到了 10 个新的神经酸衍生物（1-4、6-11）和 1 个已知化合物（5）。通过广泛的光谱分析，包括 1D 和 2D NMR 实验，确定了它们的结构。对化合物 3、4、9、10 和 11 进行了细胞毒性评估，针对的细胞系包括 A549、H460、Hela、MCF-7、Caco2 和 HepG2 人癌细胞系。
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