Department of Infectious Diseases, Oslo University Hospital and University of Oslo, Oslo, Norway.
Am J Trop Med Hyg. 2013 Feb;88(2):397-404. doi: 10.4269/ajtmh.12-0551. Epub 2013 Jan 16.
We performed a descriptive analysis of acute and potentially life-threatening tropical diseases among 82,825 ill western travelers reported to GeoSentinel from June of 1996 to August of 2011. We identified 3,655 patients (4.4%) with a total of 3,666 diagnoses representing 13 diseases, including falciparum malaria (76.9%), enteric fever (18.1%), and leptospirosis (2.4%). Ninety-one percent of the patients had fever; the median time from travel to presentation was 16 days. Thirteen (0.4%) patients died: 10 with falciparum malaria, 2 with melioidosis, and 1 with severe dengue. Falciparum malaria was mainly acquired in West Africa, and enteric fever was largely contracted on the Indian subcontinent; leptospirosis, scrub typhus, and murine typhus were principally acquired in Southeast Asia. Western physicians seeing febrile and recently returned travelers from the tropics need to consider a wide profile of potentially life-threatening tropical illnesses, with a specific focus on the most likely diseases described in our large case series.
我们对 1996 年 6 月至 2011 年 8 月间向 GeoSentinel 报告的 82825 名患病西方旅行者的急性和潜在危及生命的热带疾病进行了描述性分析。我们共发现 3655 名患者（4.4%），总计 3666 例诊断，涉及 13 种疾病，包括恶性疟（76.9%）、肠热病（18.1%）和钩端螺旋体病（2.4%）。91%的患者有发热；从旅行到就诊的中位时间为 16 天。13 名（0.4%）患者死亡：10 名死于恶性疟，2 名死于类鼻疽，1 名死于重症登革热。恶性疟主要在西非获得，肠热病主要在印度次大陆获得；钩端螺旋体病、丛林斑疹伤寒和鼠型斑疹伤寒主要在东南亚获得。看到来自热带地区发热和近期返回的旅行者的西方医生需要考虑广泛的潜在危及生命的热带疾病，特别是我们的大型病例系列中描述的最可能的疾病。
