Department of Orthopedics and Rehabilitation, Oregon Health and Science University, Portland, OR 97239, USA.
Spine (Phila Pa 1976). 2013 Aug 1;38(17):1508-15. doi: 10.1097/BRS.0b013e318285f05a.
Prospective cohort study.
To assess the impact of postoperative post-traumatic stress disorder (PTSD) symptoms on clinical outcomes after lumbar arthrodesis.
Postoperative PTSD symptoms occur among many patients who underwent elective lumbar fusion. Although adverse impact of preoperative depression and psychiatric distress has been described, no reports have assessed the impact of postoperative PTSD symptoms on clinical outcomes after lumbar arthrodesis.
Seventy-three patients undergoing elective lumbar spinal arthrodesis completed the PTSD Checklist-Civilian Version (PCL-C) at 3, 6, 9, and 12 months postoperatively. Short-Form 36 and the Oswestry Disability Index (ODI) were completed preoperatively and at 1 year postoperatively. Impact of postoperative PTSD symptoms, preoperative psychiatric diagnoses, and mental composite scores on clinical outcome scores and likelihood of reaching minimal clinically important difference for ODI and physical composite score (PCS) was evaluated.
PTSD symptoms were reported in 22% of the cohort, with significantly reduced surgical benefit as measured by final (P < 0.0001 and P = 0.003) and total change (P = 0.013 and P = 0.032) in ODI and PCS scores, respectively. Likelihood of reaching minimal clinically important difference for both ODI and PCS was also reduced for patients reporting PTSD symptoms (P = 0.009 and P = 0.001, respectively). A preoperative psychiatric diagnosis correlated only with final ODI score (P = 0.008). Preoperative mental composite scores were significantly correlated with final ODI and PCS scores, as well as final change from preoperative and likelihood of reaching minimal clinically important difference for PCS, but not for ODI scores.
Postoperative psychological distress was strongly correlated with reduced clinical benefit among patients who underwent elective lumbar arthrodesis, and seemed to be a stronger predictor of reduced clinical benefit than either major psychiatric diagnosis or preoperative mental composite scores. Efforts to reduce postoperative psychological distress may offer an opportunity to enhance patient reported clinical outcomes from elective spine surgery.
前瞻性队列研究。
评估腰椎关节融合术后创伤后应激障碍(PTSD)症状对临床结果的影响。
许多接受选择性腰椎融合术的患者都会出现术后 PTSD 症状。尽管已经描述了术前抑郁和精神困扰的不良影响,但尚无报道评估腰椎关节融合术后 PTSD 症状对临床结果的影响。
73 例接受择期腰椎脊柱关节融合术的患者在术后 3、6、9 和 12 个月时使用平民版 PTSD 检查表(PCL-C)进行评估。术前和术后 1 年完成简明 36 项健康调查量表(SF-36)和 Oswestry 残疾指数(ODI)。评估术后 PTSD 症状、术前精神科诊断和心理综合评分对临床结果评分以及达到 ODI 和身体成分评分(PCS)最小临床重要差异的可能性的影响。
该队列中有 22%的患者报告存在 PTSD 症状,最终(P < 0.0001 和 P = 0.003)和总变化(P = 0.013 和 P = 0.032)ODI 和 PCS 评分的手术获益显著降低。报告 PTSD 症状的患者达到 ODI 和 PCS 最小临床重要差异的可能性也降低(P = 0.009 和 P = 0.001)。术前精神科诊断仅与最终 ODI 评分相关(P = 0.008)。术前心理综合评分与最终 ODI 和 PCS 评分以及最终与术前相比的变化和达到 PCS 最小临床重要差异的可能性显著相关,但与 ODI 评分无关。
腰椎关节融合术后心理困扰与接受择期腰椎关节融合术的患者临床获益减少密切相关,且似乎比主要精神科诊断或术前心理综合评分更能预测临床获益减少。减少术后心理困扰的努力可能为提高择期脊柱手术患者报告的临床结果提供机会。
2 级。