Department of Physiology, College of Medicine, King Saud University, P.O. Box 2925, Riyadh, 11461, Kingdom of Saudi Arabia.
Int J Environ Res Public Health. 2013 Jan 16;10(1):390-8. doi: 10.3390/ijerph10010390.
This study aimed to determine the effect of long term exposure to cement dust on lung function in non-smoking cement mill workers. This is a cross-sectional study of respiratory functions. Spirometry was performed in 100 apparently healthy volunteers; 50 non-smoking cement mill workers and 50 non-smoking un-exposed subjects. Based on the duration of exposure, cement mill workers were divided into three groups, less than 5, 5-10 and greater than 10 years. All subjects were individually matched for age, height, weight, and socioeconomic status. Pulmonary function test was performed by using an electronic spirometer. Significant reduction was observed in the mean values of Forced Vital Capacity (FVC), Forced Expiratory Volume in one second (FEV(1)), Peak Expiratory Flow (PEF) and Maximal Voluntary Ventilation in cement mill workers who had been working in the cement industry for more than 10 years compared to their matched un-exposed group. Lung functions in cement mill workers were significantly impaired and results show a long term duration response effect of years of exposure to cement dust on lung functions.
本研究旨在探讨长期接触水泥粉尘对水泥行业中不吸烟工人肺功能的影响。这是一项关于呼吸系统功能的横断面研究。对 100 名健康志愿者(50 名不吸烟的水泥工人和 50 名未接触水泥粉尘的非暴露者)进行了肺功能检查。根据接触时间的长短,水泥工人被分为三组,分别为接触时间小于 5 年、5-10 年和大于 10 年。所有受试者在年龄、身高、体重和社会经济地位方面进行了个体匹配。肺功能检查采用电子肺活量计进行。与未接触水泥粉尘的对照组相比,接触水泥粉尘超过 10 年的水泥工人的用力肺活量(FVC)、一秒用力呼气量(FEV1)、呼气峰流速(PEF)和最大自主通气量的平均值显著降低。水泥工人的肺功能明显受损,结果表明,接触水泥粉尘的时间与肺功能的损害之间存在长期的剂量-效应关系。