NYU School of Medicine, NYU Diabetes and Endocrine Associates, 345 East 37th Street, Suite 313, New York, NY 10016, USA.
Endocrine. 2013 Aug;44(1):66-9. doi: 10.1007/s12020-013-9873-6. Epub 2013 Jan 17.
Diagnosis of dysglycemic states is likely delayed as current diagnostic criteria apply absolute threshold values to a process that is continuous. The importance of this relates to forestalling opportunities for earlier diagnosis when prevention and reversibility are more likely to occur by preventing further β cell dysfunction. Although the optimal method for earlier identification of individuals at risk remains uncertain, the paper suggests novel approaches.
由于目前的诊断标准将绝对阈值应用于连续的过程,因此可能会延迟对糖代谢状态异常的诊断。这一点很重要,因为通过防止进一步的β细胞功能障碍,可以更早地发现个体,并更有可能进行预防和逆转,从而预防进一步的β细胞功能障碍。虽然更早识别高危个体的最佳方法仍不确定,但本文提出了一些新的方法。