Department of Chemistry, Center for Self-assembly and Complexity, Polymer Research Institute, Pohang University of Science and Technology (POSTECH), Pohang, 790-784, Republic of Korea.
Chem Commun (Camb). 2013 Feb 21;49(15):1545-7. doi: 10.1039/c2cc38510d.
A photoresponsive drug releasing system based on mesoporous silica nanoparticles (MSN) was developed. A model drug was decorated on the surfaces via singlet oxygen sensitive linkers and a singlet oxygen-generating photosensitizer was loaded in the mesopores of the MSN. An on-demand drug releasing system was successfully developed by irradiation with long-wavelength light.
基于介孔硅纳米粒子 (MSN) 开发了一种光响应药物释放系统。通过单线态氧敏感连接物修饰模型药物，并将单线态氧产生的光敏剂装载到 MSN 的介孔中。通过长波长光照射成功开发了一种按需药物释放系统。
