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Updates on role of human recombinant activated protein C in patients with sepsis and severe sepsis: Changed scenario after PROWESS SHOCK trial.

作者信息

Shukla Aparna

机构信息

Integral Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

出版信息

Indian J Anaesth. 2012 Nov;56(6):597-8. doi: 10.4103/0019-5049.104597.

DOI:10.4103/0019-5049.104597
PMID:23325958
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3546260/
Abstract
摘要

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本文引用的文献

1
Withdrawal of 'Xigris' from the market: old and new lessons.
J Epidemiol Community Health. 2012 Jul;66(7):571-2. doi: 10.1136/jech-2012-200977. Epub 2012 Mar 23.
2
Role of human recombinant activated protein C and low dose corticosteroid therapy in sepsis.重组人活化蛋白C及小剂量皮质类固醇疗法在脓毒症中的作用
Indian J Anaesth. 2010 Nov;54(6):496-503. doi: 10.4103/0019-5049.72637.
3
Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shock.一项关于活化蛋白C用于持续性感染性休克的多国安慰剂对照试验的设计、实施、分析及报告。
Intensive Care Med. 2008 Nov;34(11):1935-47. doi: 10.1007/s00134-008-1266-6. Epub 2008 Oct 7.
4
Human recombinant activated protein C for severe sepsis.用于严重脓毒症的重组人活化蛋白C
Cochrane Database Syst Rev. 2008 Jan 23(1):CD004388. doi: 10.1002/14651858.CD004388.pub3.
5
Drotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trial.重组人活化蛋白C用于儿童严重脓毒症治疗:一项多中心III期随机对照试验
Lancet. 2007 Mar 10;369(9564):836-843. doi: 10.1016/S0140-6736(07)60411-5.
6
Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death.重组人活化蛋白C用于严重脓毒症且死亡风险较低的成人患者。
N Engl J Med. 2005 Sep 29;353(13):1332-41. doi: 10.1056/NEJMoa050935.
7
Efficacy and safety of recombinant human activated protein C for severe sepsis.重组人活化蛋白C治疗严重脓毒症的疗效与安全性
N Engl J Med. 2001 Mar 8;344(10):699-709. doi: 10.1056/NEJM200103083441001.