Department of Medicine, Surgery, Dentistry, University of Milan Medical School, Division of Pathology, AO San Paolo and Fondazione IRCCS Policlinico Mangiagalli and Regina Elena, Milan, Italy.
Acta Otorhinolaryngol Ital. 2012 Oct;32(5):336-8.
Extracranial meningiomas of the head and neck region are rare neoplasms, the majority being a secondary location of a primary intracranial tumour. We herewith report three rare cases of extracranial meningiomas, located in the temporal muscle, parotid gland and nasal cavity, together with complete pathological, immunohistochemical and ultrastructural studies. Prognosis of this tumour is generally excellent. Surgical excision is the treatment of choice, with no need for further treatment; nevertheless, differential diagnosis must consider other more common tumours of the head and neck and be based on histopathologic examination and relative techniques, including examination of frozen sections. This procedure is particularly useful assessing surgical treatment and should be performed whenever possible to exclude the malignant nature of the lesion and avoid over-treatment. All three patients underwent surgery and are alive and disease-free.
头部和颈部颅外脑膜瘤是罕见的肿瘤，大多数是原发性颅内肿瘤的继发部位。我们在此报告三例罕见的颅外脑膜瘤病例，位于颞肌、腮腺和鼻腔，同时进行了完整的病理、免疫组织化学和超微结构研究。该肿瘤的预后通常很好。手术切除是首选治疗方法，无需进一步治疗；然而，鉴别诊断必须考虑头颈部更常见的其他肿瘤，并基于组织病理学检查和相关技术，包括冷冻切片检查。该程序对于评估手术治疗特别有用，应尽可能进行以排除病变的恶性性质并避免过度治疗。所有三名患者均接受了手术治疗，目前无病生存。
