Rege Inara Carneiro Costa, Garcia Robson Rodrigues, Mendonça Elismauro Francisco
Paulista University, Goiânia, Goiás, Brazil.
Stomatologic Science Department, Federal University of Goiás, Goiânia, Goias, Brazil.
Head Neck Pathol. 2017 Dec;11(4):561-566. doi: 10.1007/s12105-017-0813-2. Epub 2017 Apr 11.
Meningiomas are benign extraaxial tumors of the central nervous system (CNS). Extracranial meningiomas are extremely rare (2%) and can develop as a direct extension from a primary intracranial meningioma or as true primary extracranial meningioma originating from ectopic arachnoid cells. Only eight cases of primary meningioma in the jaw have been reported to date. Extracranial meningiomas are frequently misdiagnosed, resulting in inappropriate clinical management. The aim of this article was to describe the case of a man with an asymptomatic swelling in the right retromolar area over a period of 2 months. Cone beam computed tomography was performed to determine the extension and involvement of the adjacent structures. Histopathological findings and immunohistochemical analysis aided in the diagnosis of primary extracranial meningioma in the mandible and several aspects of this unusual neoplasm are reviewed. The treatment of choice was a partial resection of the mandible and reconstruction with autogenous iliac tricortical bone. Five years after surgery, the patient remains free of disease.
脑膜瘤是中枢神经系统（CNS）的良性轴外肿瘤。颅外脑膜瘤极为罕见（2%），可由原发性颅内脑膜瘤直接蔓延发展而来，或由异位蛛网膜细胞形成真正的原发性颅外脑膜瘤。迄今为止，仅报道过8例颌骨原发性脑膜瘤病例。颅外脑膜瘤常被误诊，导致临床处理不当。本文旨在描述一名男性患者，其右磨牙后区出现无症状肿胀长达2个月。进行锥形束计算机断层扫描以确定病变范围及相邻结构受累情况。组织病理学检查结果及免疫组化分析有助于诊断下颌骨原发性颅外脑膜瘤，并对这种罕见肿瘤的几个方面进行了回顾。治疗方案为下颌骨部分切除并采用自体髂骨三皮质骨重建。术后5年，患者无疾病复发。
