泼尼松龙治疗放射性出血性胃炎 1 例报告
Treatment of radiation-induced hemorrhagic gastritis with prednisolone: a case report.
机构信息
Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
出版信息
World J Gastroenterol. 2012 Dec 28;18(48):7402-4. doi: 10.3748/wjg.v18.i48.7402.
Abstract
Radiation-induced gastritis is an infrequent cause of gastrointestinal bleeding. It is a serious complication arising from radiation therapy, and the standard treatment method has not been established. The initial injury is characteristically acute inflammation of gastric mucosa. We presented a 46-year-old male patient with hemorrhagic gastritis induced by external radiotherapy for metastatic retroperitoneal lymph node of hepatocellular carcinoma. The endoscopic examination showed diffuse edematous hyperemicmucosa with telangiectasias in the whole muscosa of the stomach and duodenal bulb. Multiple hemorrhagic patches with active oozing were found over the antrum. Anti-secretary therapy was initiated for hemostasis, but melena still occurred off and on. Finally, he was successfully treated by prednisolone therapy. We therefore strongly argue in favor of perdnisolone therapy to effectively treat patients with radiation-induced hemorrhagic gastritis.
摘要
放射性胃炎是胃肠道出血的一个不常见原因。它是放射治疗引起的严重并发症，尚未确立标准的治疗方法。最初的损伤特征为急性胃黏膜炎症。我们报告了 1 例 46 岁男性患者，因肝癌腹膜后淋巴结转移行外照射放疗后出现出血性胃炎。内镜检查显示整个胃和十二指肠球部黏膜弥漫性水肿充血，黏膜可见毛细血管扩张。胃窦部可见多处出血斑，有活动性渗血。给予抑酸治疗止血，但仍间断出现黑便。最终，泼尼松龙治疗取得成功。因此，我们强烈主张使用泼尼松龙治疗来有效治疗放射性出血性胃炎患者。
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