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患有神经疾病时患抑郁症的风险。

The risk of developing depression when suffering from neurological diseases.

作者信息

Thielscher C, Thielscher S, Kostev K

机构信息

FOM University of Applied Sciences, Essen, Germany.

出版信息

Ger Med Sci. 2013;11:Doc02. doi: 10.3205/000170. Epub 2013 Jan 14.

DOI:10.3205/000170
PMID:23326249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3546419/
Abstract

AIM OF THE STUDY

To investigate the comorbidity of Alzheimer's/dementia, epilepsy, multiple sclerosis and Parkinson's with depression.

METHODS

42,914 patients who were newly diagnosed with the four comorbid diseases were included in the study. We analyzed how many of these patients developed depression within five years.

RESULTS

Between 21% (males with epilepsy) and 39% (women with Parkinson's)/44% (Alzheimer's patients under 60 years) developed depression within five years.

CONCLUSION

We recommend routine checks for depression in patients diagnosed with one of these diseases, especially in the most comorbid ones.

摘要

研究目的

调查阿尔茨海默病/痴呆症、癫痫、多发性硬化症和帕金森病与抑郁症的共病情况。

方法

本研究纳入了42914例新诊断出患有这四种共病疾病的患者。我们分析了这些患者中有多少人在五年内患上了抑郁症。

结果

在五年内,21%(男性癫痫患者)至39%(女性帕金森病患者)/44%(60岁以下阿尔茨海默病患者)的患者患上了抑郁症。

结论

我们建议对被诊断患有这些疾病之一的患者进行抑郁症的常规检查,尤其是在共病情况最严重的患者中。

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[How do general practitioners deal with patients they do not consider to be depressed but who are classified as such according the PHQ-9?].全科医生如何处理他们认为没有抑郁但根据PHQ-9被归类为抑郁的患者?
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Pathogenic mechanisms of depression in multiple sclerosis.多发性硬化症中抑郁的发病机制。
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Depression in dementia: epidemiology, mechanisms, and treatment.痴呆症中的抑郁:流行病学、机制与治疗。
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