Kafkaslı Ayşe, Türkçüoğlu Ilgın, Turhan Uğur
Department of Obstetrics and Gynecology, İnönü University School of Medicine, Malatya, Turkey.
J Matern Fetal Neonatal Med. 2013 Jun;26(9):936-40. doi: 10.3109/14767058.2013.766688. Epub 2013 Feb 12.
To compare the maternal and fetal characteristics and perinatal outcome in mild and severe preeclampsia cases with and without uterine artery Doppler abnormalities.
Two hundred and fifty-nine mild and severe preeclampsia cases were evaluated retrospectively. Doppler measurements were done in the section where uterine artery raised from the hypogastric artery. Pulsatility index above the 95th percentile of the corresponding gestational age was accepted as abnormal.
In mild and severe preeclampsia cases with abnormal Doppler (AD), the rate of intrauterine growth restriction, preterm birth and low birth weight was higher than, but the neonatal intensive care unit stay was similar to the cases with normal Doppler. Base excess was higher in the AD group, in mild and severe preeclampsia. The rate of low Apgar score at 5 min and perinatal mortality was higher in the AD group, in the mild preeclampsia. The strongest independent predictor of the perinatal morbidity and mortality was the presence of prematurity and of the prematurity was the presence of abnormal uterine artery Doppler.
Maternal and perinatal morbidity and perinatal mortality increase in mild to severe preeclampsia cases with abnormal uterine artery Doppler. The abnormal uterine artery Doppler increases the morbidity and mortality by increasing the risk of prematurity.
比较伴或不伴子宫动脉多普勒异常的轻度和重度子痫前期病例的母婴特征及围产期结局。
回顾性评估259例轻度和重度子痫前期病例。在子宫动脉从腹下动脉发出处进行多普勒测量。将相应孕周第95百分位数以上的搏动指数视为异常。
在多普勒异常（AD）的轻度和重度子痫前期病例中，胎儿生长受限、早产和低出生体重的发生率高于多普勒正常的病例，但新生儿重症监护病房住院时间与之相似。在轻度和重度子痫前期中，AD组的碱剩余更高。在轻度子痫前期中，AD组5分钟时阿氏评分低及围产期死亡率更高。围产期发病率和死亡率最强的独立预测因素是早产的存在，而早产的存在是子宫动脉多普勒异常。
子宫动脉多普勒异常的轻度至重度子痫前期病例的孕产妇及围产期发病率和围产期死亡率增加。子宫动脉多普勒异常通过增加早产风险而增加发病率和死亡率。
