早发型和晚发型子痫前期的临床和围产结局比较。
Comparison of clinical and perinatal outcomes in early- and late-onset preeclampsia.
机构信息
Cerrahpasa Tip Fakultesi, Kadin Hastaliklari ve Dogum Anabilim Dali, Istanbul Universitesi, Kocamustafapasa, 34750, Istanbul, Turkey,
出版信息
Arch Gynecol Obstet. 2014 Jul;290(1):53-7. doi: 10.1007/s00404-014-3176-x. Epub 2014 Feb 19.
PURPOSE
To compare the clinical and laboratory findings and maternal-perinatal outcomes between women with early-onset preeclampsia (EO-PE) and late-onset preeclampsia (LO-PE).
METHODS
One hundred and fifty-four women with preeclampsia (PE) who delivered in our clinic were included in the study. Perinatal and obstetric outcomes were evaluated.
RESULTS
The incidence of abnormal uterine artery (UtA) velocity waveform was significantly higher in the EO-PE group (71.4 vs 30.1 %) (p < 0.001). The incidences of small-for-gestational age, oligohydramnios, Apgar score <7 at 5 min, stillbirth and early neonatal death rates were significantly higher in women with EO-PE compared to LO-PE (p < 0.01). Maternal complications were only recorded in women with severe PE.
CONCLUSION
EO-PE, especially with abnormal UtA Doppler findings defines a placentation abnormality with higher perinatal adverse outcomes.
目的
比较早发型子痫前期（EO-PE）和晚发型子痫前期（LO-PE）患者的临床和实验室检查结果及母婴围生结局。
方法
本研究纳入了 154 例在我院分娩的子痫前期（PE）患者，评估了围生期和产科结局。
结果
EO-PE 组异常子宫动脉（UtA）血流速度波形的发生率显著更高（71.4% vs 30.1%）（p < 0.001）。与 LO-PE 组相比，EO-PE 患者的胎儿生长受限、羊水过少、5 分钟时 Apgar 评分 <7、死胎和新生儿早期死亡率的发生率显著更高（p < 0.01）。仅在重度 PE 患者中记录了母体并发症。
结论
EO-PE 尤其是伴有异常 UtA 多普勒表现的患者，其胎盘着床异常，围生期不良结局更高。
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