Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH 44195, USA.
Semin Diagn Pathol. 2013 Feb;30(1):95-109. doi: 10.1053/j.semdp.2012.01.005.
Molecular techniques are increasingly important in the practice of surgical pathology. In soft tissue tumors, there are a number of tumors with recurring cytogenetic abnormalities. Knowledge of these abnormalities has furthered our understanding of these tumors and has also allowed development of molecular techniques to aid in the diagnosis. This review will focus on mesenchymal tumors with specific cytogenetic abnormalities that may present as a superficial tumor of the dermis or subcutis.
分子技术在外科病理学实践中变得越来越重要。在软组织肿瘤中，有许多肿瘤具有反复出现的细胞遗传学异常。对这些异常的了解不仅加深了我们对这些肿瘤的认识，而且还促使开发了分子技术以辅助诊断。本文将重点介绍可能表现为真皮或皮下浅表肿瘤的具有特定细胞遗传学异常的间叶性肿瘤。
