Ellouadghiri A, Afifi Y, Mansouri F, Hassam B, Senouci K
Service de dermatologie, CHU Ibn Sina, place Beniznassen, Souissi, 10000 Rabat, Maroc.
Ann Dermatol Venereol. 2013 Jan;140(1):36-40. doi: 10.1016/j.annder.2012.09.011. Epub 2012 Dec 14.
Sarcoidosis is a multisystem granulomatous disease of unknown aetiology. Tongue involvement is extremely rare. Herein we report a new case.
A 65-year-old woman presented with a 6-month history of painless multiple nodules on the tongue. The patient also complained of xerostomia. Besides nodules on the tongue, physical examination revealed erythematous nodules on the dorsum of the hands and feet. A diagnosis of sarcoidosis with tongue, cutaneous and salivary gland involvement was made on the basis of these findings and further investigations performed. The patient's condition showed improvement with partial regression of tongue lesions after oral steroid therapy.
Tongue involvement in sarcoidosis is exceedingly rare. It may be isolated or part of a generalized multisystem sarcoidosis. Nodules, indurations and swelling are the most common clinical manifestations. Management of tongue sarcoidosis is not consensual. Oral corticosteroids appear to be the most effective therapy.
Sarcoidosis of the tongue should be considered when chronic unexplained nodules are noted. Diagnosis can easily be confirmed by a histological examination of mucosal biopsy.
结节病是一种病因不明的多系统肉芽肿性疾病。累及舌头极为罕见。在此我们报告一例新病例。
一名65岁女性，有6个月无痛性舌部多发结节病史。患者还主诉口干。除舌部结节外，体格检查发现手背和足背有红斑性结节。根据这些发现及进一步检查，诊断为结节病累及舌、皮肤和唾液腺。口服类固醇治疗后，患者病情改善，舌部病变部分消退。
结节病累及舌头极为罕见。它可能是孤立的，也可能是全身性多系统结节病的一部分。结节、硬结和肿胀是最常见的临床表现。舌部结节病的治疗尚无共识。口服皮质类固醇似乎是最有效的治疗方法。
当发现慢性不明原因的结节时，应考虑舌部结节病。通过黏膜活检的组织学检查可轻松确诊。
