Institute of Nuclear Medicine, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2013 Jan;17(1):56-68.
This study was designed to review published data regarding the clinical usefulness of iodine-123-meta-iodobenzyl-guanidine (MIBG) scintigraphy in evaluating the effectiveness of pharmacological treatments in patients with heart failure (HF).
A comprehensive computer literature search of the PubMed/MEDLINE and Embase databases was conducted to find relevant published articles about the clinical usefulness of MIBG scintigraphy in evaluating the effectiveness of pharmacological treatments in patients with HF.
Thirty-three studies, comprising a total sample size of 1124 patients with HF, were included in this review. Main findings of the included studies are presented.
Myocardial innervation imaging using MIBG scintigraphy can be successfully used to assess changes in cardiac sympathetic neuronal function caused by several pharmacological interventions in patients with HF.
本研究旨在回顾有关碘-123-间位碘苄胍（MIBG）闪烁显像在评估心力衰竭（HF）患者药物治疗效果方面的临床应用价值的已发表数据。
通过对 PubMed/MEDLINE 和 Embase 数据库进行全面的计算机文献检索，查找有关 MIBG 闪烁显像在评估 HF 患者药物治疗效果方面的临床应用价值的相关已发表文章。
本综述纳入了 33 项研究，共计 1124 例 HF 患者。纳入研究的主要发现如下。
使用 MIBG 闪烁显像进行心肌神经支配成像可以成功地用于评估 HF 患者接受几种药物干预后心脏交感神经元功能的变化。
