Llacer J, Schmidt J B, Tobias C A
Engineering Division, Lawrence Berkeley Laboratory, California 94720.
Med Phys. 1990 Mar-Apr;17(2):158-62. doi: 10.1118/1.596537.
Accelerated heavy-ion beams used in biological and medical research are often utilized in conjunction with absorbers which lead to the fragmentation of the beam. The BERKLET, initially a two-stage solid-state telescope detector, was designed to make rapid, on-line energy and linear energy transfer (LET) measurements of individual particles in a heavy-ion beam, thus allowing characterization of fragmented beams. From data collected with the BERKLET, one is able to determine a number of important parameters. These include: residual energy and LET histograms for the full beam and for the individual Z components, relative number of particles with a given Z, and dose and track average LET's for the full beam and for the individual Z's. Improvements to the BERKLET design and changes in data analysis are discussed and contrasted with the results of an earlier BERKLET configuration. The most notable improvements are the addition of a thin scintillation detector for improved LET measurement, a tenfold improvement in the dynamic range of the event discriminator, reported here as 1:2000, and dual high-and low-gain amplification of the LET signals, permitting the identification of particles with Z's ranging from 12 down to 1.
生物和医学研究中使用的加速重离子束通常与吸收体一起使用,这会导致束流的碎片化。BERKLET最初是一种两级固态望远镜探测器,旨在对重离子束中的单个粒子进行快速在线能量和线能量转移(LET)测量,从而能够对碎片化束流进行表征。根据用BERKLET收集的数据,可以确定许多重要参数。这些参数包括:全束流以及各个Z分量的剩余能量和LET直方图、具有给定Z的粒子的相对数量、全束流以及各个Z的剂量和径迹平均LET。讨论了BERKLET设计的改进和数据分析的变化,并与早期BERKLET配置的结果进行了对比。最显著的改进包括增加了一个薄闪烁探测器以改进LET测量、事件鉴别器的动态范围提高了十倍(此处报告为1:2000)以及LET信号的双高增益和低增益放大,从而能够识别Z值范围从12到1的粒子。