Pd(II)催化的通过 C-H 键活化的苯乙酰胺与α-氧代羧酸的脱羧酰化反应。
Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C-H bond activation.
机构信息
School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
出版信息
Chem Commun (Camb). 2013 Feb 25;49(16):1654-6. doi: 10.1039/c3cc38764j.
PMID:23334232
Abstract
A palladium-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C-H bond activation is described. This protocol provides efficient access to a range of ortho-acyl phenylacetamides, which can be easily converted to 3-isochromanone derivatives.
摘要
钯催化的通过 C-H 键活化的苯乙酰胺与α-氧代羧酸的脱羧酰化反应被描述。该方案提供了一种有效获得一系列邻酰基苯乙酰胺的方法，这些化合物可以很容易地转化为 3-异苯并呋喃酮衍生物。
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