Department of Botany, Canadian Institute for Advanced Research, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4.
Brief Funct Genomics. 2013 Sep;12(5):454-6. doi: 10.1093/bfgp/els066. Epub 2013 Jan 18.
GenBank is bursting with eukaryotic RNA sequencing (RNA-Seq) results. These data are transforming our view of nuclear transcriptional architecture, but many scientists are ignoring a major component of the data: mitochondrial- and chloroplast-derived sequences. Indeed, organelle transcripts typically represent a significant proportion of the reads generated from eukaryotic RNA-Seq experiments. Here, I argue that these data are an excellent and untapped resource for investigating many aspects of organelle function and evolution.
GenBank 中充满了真核 RNA 测序（RNA-Seq）的结果。这些数据正在改变我们对核转录结构的看法，但许多科学家忽略了数据的一个主要组成部分：线粒体和叶绿体衍生序列。事实上，细胞器转录本通常代表从真核 RNA-Seq 实验中生成的reads 的很大一部分。在这里，我认为这些数据是研究细胞器功能和进化的许多方面的极好且未开发的资源。
