Department of Neurology & Neurosurgery, Faculty of Medicine, Tbilisi State University, Tbilisi, 0112, Georgia.
J Neurooncol. 2013 Apr;112(2):241-6. doi: 10.1007/s11060-013-1054-1. Epub 2013 Jan 21.
A population-based cohort study was initiated in Georgia in March 2009 to collect epidemiologic data of malignant and non-malignant primary brain tumours. During the first year, 473 incident cases were identified. For a population of 4.3 million, the annual incidence rate was 10.25 per 100,000 inhabitants, age-standardized to the year 2000 US population. Non-malignant tumours constituted about 66 % of all tumours. Males accounted for 40 % and females for 60 % of the cases. Crude incidence rates by histology were highest for meningiomas (2.92/100,000), pituitary adenoma (1.16/100,000) and glioblastomas (0.64/100,000), which was in agreement with the frequency of reported histology: meningiomas--45.2 %, pituitary adenoma--18.0 % and glioblastomas--9.9 %. The age-standardized incidence rates were higher among females than males for all primary brain tumours (11.05 vs. 8.44/100,000) as well as for individual histologies except for glioblastoma and several other neuroepithelial tumours. Some differences compared with 2004-2005 Central Brain Tumor Registry of the United States data may be explained by a higher percentage of unclassified tumours (37 %) in our study. We suggest further studies to clarify the nature of this discrepancy.
一项以人群为基础的队列研究于 2009 年 3 月在格鲁吉亚启动，旨在收集恶性和非恶性原发性脑肿瘤的流行病学数据。在第一年，确定了 473 例新发病例。在 430 万人口中，年发病率为每 10 万人 10.25 例，按 2000 年美国人口年龄标准化。非恶性肿瘤约占所有肿瘤的 66%。男性占病例的 40%，女性占 60%。按组织学分类，粗发病率最高的是脑膜瘤（2.92/10 万）、垂体腺瘤（1.16/10 万）和胶质母细胞瘤（0.64/10 万），这与报告的组织学频率一致：脑膜瘤-45.2%、垂体腺瘤-18.0%和胶质母细胞瘤-9.9%。所有原发性脑肿瘤（11.05 比 8.44/10 万）以及除胶质母细胞瘤和其他几种神经上皮肿瘤外的所有组织学类型，女性的年龄标准化发病率均高于男性。与 2004-2005 年美国中央脑肿瘤登记处的数据相比，我们研究中未分类肿瘤（37%）的比例较高，可能解释了一些差异。我们建议进一步研究以阐明这种差异的性质。
