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爱沙尼亚原发性中枢神经系统肿瘤的流行病学。

Epidemiology of primary central nervous system tumors in Estonia.

作者信息

Liigant A, Asser T, Kulla A, Kaasik A E

机构信息

Department of Neurology and Neurosurgery, University of Tartu,

出版信息

Neuroepidemiology. 2000 Nov-Dec;19(6):300-11. doi: 10.1159/000026269.

Abstract

During the period from 1986 to 1996, 1,665 cases of primary central nervous system (CNS) tumors were identified in the resident population of Estonia. Histological verification was available in 81% of the cases. Gliomas were more common in men, while meningiomas and neurinomas were more common in women. No significant difference was observed between the sexes for all primary CNS tumors. The age-specific incidence increased from the age of 30, reached a maximum in the age range of 50-69 years and declined in the elderly which may reflect under-diagnosis. The age-adjusted incidence rate for CNS tumors was 8.5/100,000 population. A comparison of our results with those of a previous study carried out in Estonia revealed a significant histology-specific increase in incidence in all age groups.

摘要

1986年至1996年期间,在爱沙尼亚常住人口中确诊了1665例原发性中枢神经系统(CNS)肿瘤。81%的病例有组织学确诊。胶质瘤在男性中更为常见,而脑膜瘤和神经鞘瘤在女性中更为常见。所有原发性中枢神经系统肿瘤在性别上未观察到显著差异。年龄别发病率从30岁开始上升,在50 - 69岁年龄组达到最高,在老年人中下降,这可能反映了诊断不足。中枢神经系统肿瘤的年龄调整发病率为每10万人口8.5例。将我们的结果与之前在爱沙尼亚进行的一项研究结果进行比较,发现在所有年龄组中,发病率均有显著的组织学特异性增加。

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